Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.47 |
| ▸ | PGR | P06401 | 5/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856628 | 0.81 | NR3C1 (0.60) | NR3C1PGRSMO | |
| SCHEMBL3847216 | 0.77 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL3855185 | 0.76 | NR3C1 (0.46) | NR3C1PGR | |
| SCHEMBL3009584 | 0.75 | NR3C1 (0.58) | NR3C1PGRSMO | |
| SCHEMBL3848875 | 0.74 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL3013580 | 0.72 | NR3C1 (0.48) | NR3C1PGR | |
| SCHEMBL4572853 | 0.72 | NR3C1 (0.56) | NR3C1PGRSMO | |
| SCHEMBL3850877 | 0.72 | NR3C1 (0.50) | NR3C1PGR | |
| SCHEMBL1362678 | 0.72 | SMO (0.64) | NR3C1PGRSMO | |
| SCHEMBL3847220 | 0.71 | NR3C1 (0.49) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102170-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-09-23 | — | — | EP | claimed |
| WO-2008070507-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-12 | — | — | WO | claimed |
| EP-2102170-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008070507-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-12 | — | — | WO | disclosed |