Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | DRD3 | P35462 | 9/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492729 | 0.87 | GPR119 (0.55) | DRD2DRD3VCP | |
| SCHEMBL3848514 | 0.86 | DRD2 (0.48) | DRD2DRD3NOTUMVCPHTR1A | |
| SCHEMBL3853616 | 0.84 | DRD2 (0.48) | DRD2DRD3VCPHTR1A | |
| SCHEMBL3844622 | 0.83 | DRD2 (0.49) | DRD2DRD3 | |
| SCHEMBL3869228 | 0.80 | GPR119 (0.54) | DRD2DRD3VCP | |
| SCHEMBL4500313 | 0.80 | CHRM4 (0.58) | DRD2DRD3NOTUM | |
| SCHEMBL3850345 | 0.79 | DRD2 (0.47) | DRD2DRD3NOTUMVCPHTR1A | |
| SCHEMBL3845294 | 0.79 | DRD2 (0.43) | DRD2DRD3VCP | |
| SCHEMBL3849026 | 0.79 | NOTUM (0.50) | DRD2DRD3NOTUMVCPHTR1A | |
| SCHEMBL14346696 | 0.79 | DRD2 (0.57) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038268-A2 | CARBONYLATED (AZA)CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007148208-A2 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2007-12-27 | — | — | WO | disclosed |