⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015869 | 1.00 | TRPA1 (0.46) | — | |
| SCHEMBL12305755 | 1.00 | — | — | |
| SCHEMBL15456193 | 0.97 | TRPA1 (0.44) | — | |
| Ammonia Solution, Strong SCHEMBL22577671 | 0.97 | TRPA1 (0.44) | — | |
| Potassium Iodide SCHEMBL27859957 | 0.93 | TRPA1 (0.41) | — | |
| Acetic Acid SCHEMBL29174291 | 0.93 | TRPA1 (0.41) | — | |
| Ether SCHEMBL6302680 | 0.89 | ALDH1A1 (0.48) | — | |
| Ethyl Bromo Acetate SCHEMBL3304713 | 0.87 | ALDH1A1 (0.71) | — | |
| SCHEMBL6432082 | 0.83 | TRPA1 (0.46) | — | |
| SCHEMBL11042898 | 0.83 | CA12 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 21262 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121698848-B | Iron complex with triazacyclononane macrocyclic skeleton, and preparation method and application thereof | Quzhou Research Institute of Zhejiang University (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122079906-A | Synthesis method of Leifenesin | — | 2026-05-26 | — | — | CN | claimed |
| CN-122059932-A | Double-functional molecular compound based on DCAF ligand-induced SHP2 protein degradation and preparation method and application thereof | 福建中医药大学 | 2026-05-19 | — | — | CN | claimed |
| CN-121471090-B | Photoresist agent based on alkynyl bridging and biphenyl structure, preparation method and application | 南开大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122059972-A | Near infrared ratio type fluorescent probe for rapidly and reversibly detecting histamine, preparation method thereof and application thereof in cell dynamic imaging | 华东师范大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122038056-A | Alkaline cleaning agent for semiconductor corrugated pipe and cleaning and drying method | 沈阳帕卡濑精有限总公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122010783-A | Synthesis method of N-Fmoc-N- (2-fluoroethyl) glycine | 康化（上海）新药研发有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122011090-A | Protein degradation targeting chimeric body targeting FGFR4 as well as preparation method and application thereof | 重庆医科大学 | 2026-05-12 | — | — | CN | claimed |
| US-20260092040-A1 | SYNTHESIS OF CYCLOPROPANE CARBOXYLIC ACIDS | PAPAIOANNOU NIKOLAOS (US) | 2026-04-02 | — | — | US | claimed |
| US-12590073-B2 | Process for the preparation of macrocyclic chelant 2,2′,2″-(10-(2-hydroxypropyl)-1,4,7,10-tetra azacyclododecane-1,4,7-triyl) triacetic acid and it's complexes with paramagnetic metal ions | BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) | 2026-03-31 | — | — | US | claimed |
| WO-1994010139-A1 | NOVEL VITAMIN D ANALOGUES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1994-05-11 | — | — | WO | claimed |
| EP-0365324-B1 | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors | AMERICAN HOME PROD (US) | 1994-05-04 | — | — | EP | claimed |
| WO-1992019591-A1 | PROCESS FOR PREPARATION OF ALPHA-ALKOXY ACETIC ACIDS AND THEIR SALTS | G.D. SEARLE & CO. (US) | 1992-11-12 | — | — | WO | claimed |
| EP-0512472-A1 | Process for preparation of alpha-alkoxy acetic acids and their salts | G.D. Searle & Co. (US) | 1992-11-11 | — | — | EP | claimed |
| US-5145992-A | Oxyalkylation of an alcohol, reaction with monoaloacetic acid and then with hydrochloic acid | G. D. SEARLE & CO. (US) | 1992-09-08 | — | — | US | claimed |
| US-5093496-A | Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-03 | — | — | US | claimed |
| EP-0458549-A1 | N-alkyl-spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-11-27 | — | — | EP | claimed |
| EP-0458551-A1 | Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-11-27 | — | — | EP | claimed |
| US-4927831-A | PREVENTION OF DIABETES MELLITUS ASSOCIATED COMPLICATIONS | AMERICAN HOME PRODUCTS (US) | 1990-05-22 | — | — | US | claimed |
| EP-0365324-A1 | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1990-04-25 | — | — | EP | claimed |