Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637006 | 0.88 | TSHR (0.35) | TSHRLMNATHRB | |
| SCHEMBL1172482 | 0.88 | TSHR (0.40) | TSHRLMNATHRB | |
| Bromide SCHEMBL3839421 | 0.85 | TSHR (0.38) | TSHRLMNATHRB | |
| SCHEMBL2286043 | 0.84 | TSHR (0.40) | TSHRLMNATHRB | |
| SCHEMBL3307844 | 0.82 | TSHR (0.35) | TSHRLMNATHRB | |
| SCHEMBL3312771 | 0.82 | — | — | |
| SCHEMBL1415172 | 0.80 | TSHR (0.39) | TSHRLMNATHRB | |
| SCHEMBL3383300 | 0.79 | — | — | |
| SCHEMBL98416 | 0.75 | TSHR (0.46) | TSHRLMNATHRB | |
| SCHEMBL385085 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979361-B1 | OXONIUM AND SULFONIUM SALTS | MERCK PATENT GMBH (DE) | 2010-11-24 | — | — | EP | claimed |
| US-8148443-B2 | Oxonium and sulfonium salts | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-04-03 | — | — | US | disclosed |
| US-8101749-B2 | Process for the preparation of onium salts with a tetrafluoroborate anion having a reduced halide content | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20110034698-A1 | Oxonium And Sulfonium Salts | IGNATYEV NIKOLAI MYKOLA | 2011-02-10 | — | — | US | disclosed |
| US-7842804-B2 | Ionic salts comprising pyrrolidinium, triazolinium, piperidinium or morpholinium cations and alkyltrifluorophosphate anions | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-11-30 | — | — | US | disclosed |
| EP-1979361-B1 | OXONIUM AND SULFONIUM SALTS | MERCK PATENT GMBH (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2253638-A2 | Fluoralkylfluorophosphate salts | Merck Patent GmbH (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-1831179-B1 | METHOD FOR THE PRODUCTION OF ONIUM SALTS WITH TETRAFLUOROBORATE ANION HAVING A REDUCED HALIDE CONTENT | MERCK PATENT GMBH (DE) | 2010-11-03 | — | — | EP | disclosed |
| US-20090253912-A1 | PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH A TETRAFLUOROBORATE ANION HAVING A REDUCED HALIDE CONTENT | MERCK PATENT GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090036628-A1 | OXONIUM AND SULFONIUM SALTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-02-05 | — | — | US | disclosed |
| EP-1979361-A2 | OXONIUM AND SULFONIUM SALTS | Merck Patent GmbH (DE) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007087949-A2 | OXONIUM AND SULFONIUM SALTS | MERCK PATENT GMBH (DE) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034698-A1 | Oxonium And Sulfonium Salts | PRDX2, SCO2, SFXN1 | TSHR 2582/4885LMNA 4215/4885THRB 3705/4885 |
| US-20090036628-A1 | OXONIUM AND SULFONIUM SALTS | SCO2, PRDX2, SFXN1 | TSHR 2551/4885LMNA 4269/4885THRB 3678/4885 |
| US-20090253912-A1 | PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH A TETRAFLUOROBORATE ANION HAVING A REDUCED HALIDE CONTENT | HCN4, PFAS, NUP205 | TSHR 489/4885LMNA 2175/4885THRB 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.