SCHEMBL384965

SCHEMBL384965

O=C(O)Nc1c[nH]c2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 13/20 0.63
GPR84 Q9NQS5 1/20 0.52
MEN1 O00255 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
KMT2A Q03164 1/20 0.51
CFTR P13569 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28736881 0.87 STING1 (0.74) STING1GPR84
SCHEMBL5894412 0.86 STING1 (0.56) STING1GPR84MEN1NPC1RAB9A
SCHEMBL4490274 0.85 STING1 (0.59) STING1GPR84
Hydrochloric Acid SCHEMBL9574627 0.84 STING1 (0.55) STING1GPR84MEN1NPC1RAB9A
SCHEMBL7543952 0.84 STING1 (0.55) STING1MEN1NPC1RAB9AKMT2A
SCHEMBL1596152 0.84 STING1 (0.61) STING1GPR84MEN1KMT2A
SCHEMBL23207192 0.83 MEN1 (0.66) STING1MEN1NPC1RAB9AKMT2A
SCHEMBL27375909 0.83 STING1 (0.78) STING1MEN1NPC1RAB9AKMT2A
SCHEMBL747027 0.81 STING1 (0.55) STING1GPR84
SCHEMBL14889338 0.81 STING1 (0.55) STING1GPR84MEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106771303-B One kind is for analyzing conveying device and its working method in heavy metal-polluted soil sample injector 徐州腾睿智能装备有限公司 2018-09-18 CN claimed
CN-106742373-A A kind of automatic charging packaging facilities and its method of work based on the exploitation of feature gingko milk beverage 徐州工程学院 2017-05-31 CN claimed
CN-106771303-A One kind is for analyzing conveying device and its method of work in heavy metal-polluted soil sample injector 徐州工程学院 2017-05-31 CN claimed
WO-2025079045-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2025-04-17 WO disclosed
EP-4463441-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM Due, Inc. (US) 2024-11-20 EP disclosed
WO-2023137041-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM DUE, INC. (US) 2023-07-20 WO disclosed
EP-4182030-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY IFM Due, Inc. (US) 2023-05-24 EP disclosed
CN-115113482-A Negative photosensitive resin composition, pattern forming method, cured film forming method, interlayer insulating film, and surface protective film 信越化学工业株式会社 2022-09-27 CN disclosed
CN-106771303-B One kind is for analyzing conveying device and its working method in heavy metal-polluted soil sample injector 徐州腾睿智能装备有限公司 2018-09-18 CN disclosed
CN-106742373-A A kind of automatic charging packaging facilities and its method of work based on the exploitation of feature gingko milk beverage 徐州工程学院 2017-05-31 CN disclosed
CN-106771303-A One kind is for analyzing conveying device and its method of work in heavy metal-polluted soil sample injector 徐州工程学院 2017-05-31 CN disclosed
US-8101748-B2 Fluorinated catharanthine derivatives, their preparation and their utilisation as Vinca dimeric alkaloid precursors PIERRE FABRE MEDICAMENT (FR) 2012-01-24 US disclosed
EP-2078017-B9 FLUORINATED CATHARANTHINE DERIVATIVES, THEIR PREPARATION AND THEIR UTILISATION AS VINCA DIMERIC ALKALOID PRECURSORS PF MEDICAMENT (FR) 2011-09-07 EP disclosed
EP-1971606-A2 2-PYRIMIDINYL PYRAZOLOPYRIDINE ERBB KINASE INHIBITORS SmithKline Beecham Corporation (US) 2008-09-24 EP disclosed
WO-2007067506-A2 2-PYRIMIDINYL PYRAZOLOPYRIDINE ERBB KINASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2007-06-14 WO disclosed
EP-0775131-A2 INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS ASTA Medica Aktiengesellschaft (DE) 1997-05-28 EP disclosed
WO-1996004266-A2 INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1996-02-15 WO disclosed
WO-1995031449-A1 NOVEL 3,5-DIMETHYLPIPERIDIN-1-YLALKYL ESTERS SANOFI (FR) 1995-11-23 WO disclosed
EP-0667857-A1 INDOLYLCARBAMATES AS ANTI-INFLAMMATORY AGENTS PFIZER INC. (US) 1995-08-23 EP disclosed
WO-1994010144-A1 INDOLYLCARBAMATES AS ANTI-INFLAMMATORY AGENTS PFIZER INC. (US) 1994-05-11 WO disclosed