Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889338 | 0.88 | STING1 (0.55) | STING1ALDH1A1ATMGPR84GAA | |
| SCHEMBL28736881 | 0.87 | STING1 (0.74) | STING1ALDH1A1ATMGPR84NR4A2 | |
| SCHEMBL384965 | 0.85 | STING1 (0.63) | STING1GPR84 | |
| SCHEMBL1596152 | 0.84 | STING1 (0.61) | STING1GPR84NR4A2CREBBP | |
| SCHEMBL2884199 | 0.84 | MAPK1 (0.63) | STING1ALDH1A1ATMKDM4EGAA | |
| SCHEMBL27522079 | 0.83 | STING1 (0.54) | STING1ALDH1A1ATMGPR84GAA | |
| SCHEMBL5894412 | 0.82 | STING1 (0.56) | STING1ALDH1A1GPR84KDM4EGAA | |
| SCHEMBL23167581 | 0.81 | STING1 (0.58) | STING1GPR84GAANR4A2CREBBP | |
| SCHEMBL9347092 | 0.81 | STING1 (0.58) | STING1GPR84GAANR4A2CREBBP | |
| SCHEMBL7543952 | 0.81 | STING1 (0.55) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160209-B | Indole group-containing compound and preparation method and application thereof | 华南师范大学 | 2024-03-29 | — | — | CN | claimed |
| CN-115093361-B | Novel indole acylhydrazone compound and preparation method and application thereof | 华南师范大学 | 2024-02-13 | — | — | CN | claimed |
| WO-2023239903-A1 | COMPOSITIONS AND METHODS FOR PREVENTING RETENTION OF PSMA-TARGETED THERAPY | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-12-14 | — | — | WO | claimed |
| EP-4103278-A1 | SMALL MOLECULE STING ANTAGONISTS | Curadev Pharma Pvt. Ltd. (IN) | 2022-12-21 | — | — | EP | claimed |
| CN-108101828-B | 3-indolyl formamide compound and preparation method thereof | 西华师范大学 | 2021-05-04 | — | — | CN | claimed |
| CN-119330982-A | Azetidine compound and medical application thereof | 中国科学院上海药物研究所 | 2025-01-21 | — | — | CN | disclosed |
| CN-117903038-A | N-ethylcarbazole-3-indolyl formylhydrazone compound and preparation method thereof | 佳木斯大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-117777004-A | Deuterated indolyl urea compound and medical application thereof | 重庆中国药科大学创新研究院 | 2024-03-29 | — | — | CN | disclosed |
| CN-117777004-A | Deuterated indolyl urea compound and medical application thereof | 重庆中国药科大学创新研究院 | 2024-03-29 | — | — | CN | disclosed |
| CN-115160209-B | Indole group-containing compound and preparation method and application thereof | 华南师范大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-117777004-A | Deuterated indolyl urea compound and medical application thereof | 重庆中国药科大学创新研究院 | 2024-03-29 | — | — | CN | disclosed |
| CN-117756698-A | Urea compound and medical application thereof as STING inhibitor | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |
| EP-0544819-B1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | ABBOTT LAB (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5459150-A | Treatment of allergies and inflammatory diseases | ABBOTT LABORATORIES (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0544819-A4 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | — | 1993-10-20 | — | — | EP | disclosed |
| CN-1076197-A | The preparation method of indole urea derivative | BEECHAM GROUP PLC (GB) | 1993-09-15 | — | — | CN | disclosed |
| CN-1076197-A | The preparation method of indole urea derivative | BEECHAM GROUP PLC (GB) | 1993-09-15 | — | — | CN | disclosed |
| EP-0544819-A1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS. | ABBOTT LAB (US) | 1993-06-09 | — | — | EP | disclosed |
| US-5095031-A | Enzyme inhibitors, antiallergens, antiinflammatory | ABBOTT LABORATORIES (US) | 1992-03-10 | — | — | US | disclosed |
| WO-1992003132-A1 | INDOLE DERIVATIVES WHICH INHIBIT LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1992-03-05 | — | — | WO | disclosed |