Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 17/20 | 0.45 |
| ▸ | DPP4 | P27487 | 16/20 | 0.45 |
| ▸ | PREP | P48147 | 15/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3851297 | 1.00 | FAP (0.45) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL5912493 | 1.00 | FAP (0.45) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL2959334 | 0.74 | FAP (0.59) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL2956816 | 0.74 | FAP (0.59) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL2956815 | 0.72 | FAP (0.54) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL5498101 | 0.67 | DPP4 (0.51) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL5498099 | 0.67 | DPP4 (0.51) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL3149737 | 0.65 | DPP4 (0.62) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL2818278 | 0.65 | DPP4 (0.62) | FAPDPP4PREPDPP8DPP9 | |
| SCHEMBL13134194 | 0.63 | FAP (0.60) | FAPDPP4PREPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576121-B2 | Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV | PHENOMIX CORPORATION (US) | 2009-08-18 | — | — | US | claimed |
| US-20060258621-A1 | PYRROLIDINE COMPOUNDS AND METHODS FOR SELECTIVE INHIBITION OF DIPEPTIDYL PEPTIDASE-IV | SINO-MED INTERNATIONAL ALLIANCE, INC. | 2006-11-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258621-A1 | PYRROLIDINE COMPOUNDS AND METHODS FOR SELECTIVE INHIBITION OF DIPEPTIDYL PEPTIDASE-IV | DPP4, DPP7, DPP3 | FAP 24/4885DPP4 1/4885PREP 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.