Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 2/20 | 0.59 |
| ▸ | CASP7 | P55210 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38503 | 1.00 | KDM4E (0.59) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL10338122 | 0.86 | TDP1 (0.57) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL27222039 | 0.84 | KDM4E (0.55) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL29364937 | 0.78 | ALDH1A1 (0.68) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL231377 | 0.78 | ALDH1A1 (0.68) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL5387299 | 0.77 | CYP19A1 (0.49) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL5387303 | 0.77 | CYP19A1 (0.49) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL713768 | 0.76 | KDM4E (0.65) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL2810654 | 0.76 | ALDH1A1 (0.65) | KDM4EKMT2ATDP1ALDH1A1MAPT | |
| SCHEMBL107833 | 0.76 | KMT2A (0.95) | KDM4EKMT2ATDP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571973-B1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & CO (US) | 2020-04-01 | — | — | EP | disclosed |
| US-8740997-B2 | Optical brighteners and compositions comprising the same | MILLIKEN & COMPANY (US) | 2014-06-03 | — | — | US | disclosed |
| US-20130281347-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY | 2013-10-24 | — | — | US | disclosed |
| US-8454711-B2 | Optical brighteners and compositions comprising the same | MILLIKEN & COMPANY (US) | 2013-06-04 | — | — | US | disclosed |
| EP-2571973-A2 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | Milliken & Company (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20120329699-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY (US) | 2012-12-27 | — | — | US | disclosed |
| US-8262744-B2 | Optical brighteners and compositions comprising the same | MILLIKEN & COMPANY (US) | 2012-09-11 | — | — | US | disclosed |
| WO-2011146604-A2 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110287999-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | MILLIKEN & COMPANY | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287999-A1 | OPTICAL BRIGHTENERS AND COMPOSITIONS COMPRISING THE SAME | DBN1, AOC1, RARB | KDM4E 3819/4885KMT2A 2905/4885TDP1 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.