SCHEMBL3850328

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3849346	0.90	MEN1 (0.72)	MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1
	SCHEMBL3134908	0.87	MEN1 (1.00)	MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1
	SCHEMBL3850365	0.85	MEN1 (0.76)	MEN1KMT2AKDM4EALDH1A1LMNA
	SCHEMBL13742157	0.83	MEN1 (0.76)	MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1
	SCHEMBL4143779	0.82	MEN1 (0.59)	MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1
	SCHEMBL3857027	0.82	MEN1 (0.70)	MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1
	SCHEMBL3851738	0.82	MEN1 (0.70)	MEN1KMT2AKDM4EALDH1A1LMNA
	SCHEMBL10018574	0.81	KMT2A (0.89)	MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1
	SCHEMBL3853314	0.81	MEN1 (0.69)	MEN1KMT2AKDM4EALDH1A1LMNA
	SCHEMBL3856200	0.81	MEN1 (0.69)	MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.