⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859216 | 0.88 | — | — | |
| SCHEMBL16081490 | 0.87 | PDE1A (0.34) | — | |
| SCHEMBL9957804 | 0.86 | LMNA (0.37) | — | |
| SCHEMBL17365402 | 0.86 | CYP2C9 (0.34) | — | |
| SCHEMBL5143428 | 0.84 | MEN1 (0.34) | — | |
| SCHEMBL3837828 | 0.83 | CHRNB2 (0.33) | — | |
| SCHEMBL3850998 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3853545 | 0.81 | CHRNB2 (0.35) | — | |
| SCHEMBL15291896 | 0.80 | TDP1 (0.44) | — | |
| SCHEMBL3836316 | 0.79 | HTT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7578855-B2 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'ORéAL S.A. (FR) | 2009-08-25 | — | — | US | claimed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | claimed |
| US-7578855-B2 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'ORéAL S.A. (FR) | 2009-08-25 | — | — | US | disclosed |
| US-7578856-B2 | Dyeing compositions comprising at least one aminopyrazolopyridine oxidation base, at least one coupler and at least one C4-C30 polyol and methods and use thereof | L'OREAL S.A. (FR) | 2009-08-25 | — | — | US | disclosed |
| US-20070136959-A1 | Composition for dyeing keratin fibers comprising at least one cationic 3-amino-pyrazolopyridine derivative, and methods of use thereof | L'OREAL S.A. (FR) | 2007-06-21 | — | — | US | disclosed |