Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942508 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBTDP1HSD17B10 | |
| SCHEMBL7112942 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBTDP1HSD17B10 | |
| SCHEMBL4891671 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRTHRBTDP1HSD17B10 | |
| SCHEMBL3446620 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBTDP1HSD17B10 | |
| SCHEMBL139709 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBTDP1HSD17B10 | |
| SCHEMBL29161121 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRTHRBTDP1HSD17B10 | |
| SCHEMBL14518186 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TSHRTHRBTDP1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28224389 | 0.75 | ALDH1A1 (0.71) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL3449037 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTHRBTDP1HSD17B10 | |
| SCHEMBL7053117 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2024-12-12 | — | — | US | disclosed |
| EP-4448536-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118401532-A | High-purity polysiloxane macromer and preparation method thereof | 盖列斯特有限公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2023113779-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2023-06-15 | — | — | US | disclosed |
| CN-103890100-B | Siloxane-based composition and solidfied material thereof with and uses thereof | CENTRAL GLASS CO.,LTD. (JP) | 2016-05-25 | — | — | CN | disclosed |
| US-9080017-B2 | Siloxane-based composition and cured product thereof, and use therefor | CENTRAL GLASS COMPANY, LIMITED (JP) | 2015-07-14 | — | — | US | disclosed |
| US-20140275445-A1 | Siloxane-Based Composition and Cured Product Thereof, and Use Therefor | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-09-18 | — | — | US | disclosed |
| CN-103890100-A | Siloxane-based composition and cured product thereof, and use therefor | CENTRAL GLASS CO LTD | 2014-06-25 | — | — | CN | disclosed |
| US-7576169-B2 | Reaction of a silica source derived from combusted organic material such as rice hull ash or pyrolysis by-products with a quaternary ammonium hydroxide compound in alcholic solvent; salt formation, quaternization; stabilization of wood | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-08-18 | — | — | US | disclosed |
| EP-1675671-A2 | FACILE SYNTHESIS OF POLYHEDRAL SILSESQUIOXANE ANIONS AND USE THEREOF | Regents of the University of Michigan (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20050142054-A1 | Facile synthesis of polyhedral silsesquioxane anions and use thereof | REGENTS OF THE UNIVERSITY OF MICHIGAN, THE | 2005-06-30 | — | — | US | disclosed |
| WO-2005039744-A2 | FACILE SYNTHESIS OF POLYHEDRAL SILSESQUIOXANE ANIONS AND USE THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-05-06 | — | — | WO | disclosed |
| US-6197988-B1 | DECOMPOSITION IN PRESENCE OF LEWIS ACID METAL HALIDE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| US-5847178-A | Method for purifying 3-methacryloxypropyldimethylhalosilanes and 3-methacryloxypropylmethyldihalosilanes | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5811565-A | TREATING MIXTURE WITH LEWIS ACID HALIDE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | SSRP1, RPLP2, RPLP1 | ALDH1A1 837/4885TSHR 1897/4885THRB 2939/4885 |
| US-20230183273-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | SSRP1, RPLP2, RPLP1 | ALDH1A1 837/4885TSHR 1897/4885THRB 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.