SCHEMBL3851271

SCHEMBL3851271

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nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TDP1 Q9NUW8 1/20 0.37
USP2 O75604 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
PDE4A P27815 1/20 0.33
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15754346 1.00 LMNA (0.39) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL599665 1.00 LMNA (0.39) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL8718435 1.00 LMNA (0.39) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL8375908 0.88 AKR1B1 (0.32) LMNAL3MBTL1AKR1B1
SCHEMBL2848010 0.80 LMNA (0.39) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL8486 0.80 LMNA (0.39) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL2316300 0.80 LMNA (0.39) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL3507128 0.79 PTPN1 (0.36) LMNAL3MBTL1TDP1PDE4A
SCHEMBL3507130 0.79 PTPN1 (0.36) LMNAL3MBTL1TDP1PDE4A
SCHEMBL1921547 0.79 PTPN1 (0.36) LMNAL3MBTL1TDP1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10494452-B2 Low-molecular-weight glycosaminoglycan derivative containing terminal 2, 5-anhydrated talose or derivative thereof JIUZHITANG CO., LTD. (CN) 2019-12-03 US claimed
EP-2985298-B1 LOW-MOLECULAR-WEIGHT FUCOSYLATED GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF JIUZHITANG CO LTD (CN) 2019-09-25 EP claimed
US-20160060364-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2, 5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) 2016-03-03 US claimed
EP-2985298-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF Kunming Institute of Botany Chinese Academy of Sciences (CN) 2016-02-17 EP claimed
CN-111484565-B Sweet wormwood polysaccharide, preparation method thereof and application thereof in preparation of anticomplement medicines 复旦大学 2022-06-07 CN disclosed
CN-111484565-A Sweet wormwood polysaccharide, preparation method thereof and application thereof in preparation of anticomplement medicines 复旦大学 2020-08-04 CN disclosed
US-10494452-B2 Low-molecular-weight glycosaminoglycan derivative containing terminal 2, 5-anhydrated talose or derivative thereof JIUZHITANG CO., LTD. (CN) 2019-12-03 US disclosed
EP-2985298-B1 LOW-MOLECULAR-WEIGHT FUCOSYLATED GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF JIUZHITANG CO LTD (CN) 2019-09-25 EP disclosed
US-20160060364-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2, 5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) 2016-03-03 US disclosed
EP-2985298-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2,5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF Kunming Institute of Botany Chinese Academy of Sciences (CN) 2016-02-17 EP disclosed
EP-2049125-A2 TREATMENT OF CANCER WITH 2-DEOXYGALACTOSE Landau, Bernard R. (US) 2009-04-22 EP disclosed
WO-2007098183-A2 TREATMENT OF CANCER WITH 2-DEOXYGALACTOSE LANDAU BERNARD R (US) 2007-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160060364-A1 LOW-MOLECULAR-WEIGHT GLYCOSAMINOGLYCAN DERIVATIVE CONTAINING TERMINAL 2, 5-ANHYDRATED TALOSE OR DERIVATIVE THEREOF FUCA2, PLG, FUCA1 LMNA 1208/4885L3MBTL1 2651/4885TDP1 2145/4885
US-10494452-B2 Low-molecular-weight glycosaminoglycan derivative containing terminal 2, 5-anhydrated talose or derivative thereof FUCA2, PLG, FUCA1 LMNA 1208/4885L3MBTL1 2651/4885TDP1 2145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.