Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3507128 | 1.00 | PTPN1 (0.36) | PTPN1LMNAL3MBTL1MPITDP1 | |
| SCHEMBL5789757 | 1.00 | PTPN1 (0.36) | PTPN1LMNAL3MBTL1MPITDP1 | |
| SCHEMBL1921547 | 1.00 | PTPN1 (0.36) | PTPN1LMNAL3MBTL1MPITDP1 | |
| SCHEMBL139867 | 0.89 | PTPN1 (0.38) | PTPN1MPI | |
| SCHEMBL6429913 | 0.89 | PTPN1 (0.38) | PTPN1MPI | |
| SCHEMBL29408337 | 0.83 | LMNA (0.42) | PTPN1LMNAL3MBTL1MPITDP1 | |
| SCHEMBL29431969 | 0.83 | LMNA (0.42) | PTPN1LMNAL3MBTL1MPITDP1 | |
| SCHEMBL7639200 | 0.81 | PTPN1 (0.38) | PTPN1MPI | |
| SCHEMBL3851271 | 0.79 | LMNA (0.39) | LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL599665 | 0.79 | LMNA (0.39) | LMNAL3MBTL1TDP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526326-A1 | NOVEL ENGINEERED AND CHIMERIC NUCLEASES | The Regents of The University of Colorado, A Body Corporate (US) | 2019-08-21 | — | — | EP | disclosed |
| WO-2018071672-A1 | NOVEL ENGINEERED AND CHIMERIC NUCLEASES | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2018-04-19 | — | — | WO | disclosed |
| EP-1311661-B1 | ENHANCED HOMOLOGOUS RECOMBINATION MEDIATED BY LAMBDA RECOMBINATION PROTEINS | US GOV HEALTH & HUMAN SERV (US) | 2012-10-03 | — | — | EP | disclosed |
| US-20100267093-A1 | ENHANCED HOMOLOGOUS RECOMBINATION MEDIATED BY LAMBDA RECOMBINATION PROTEINS | THE GOV. OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPT OF HEALTH AND HUMAN SERVICES | 2010-10-21 | — | — | US | disclosed |
| US-7144734-B2 | Enhanced homologous recombination mediated by lambda recombination proteins | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-12-05 | — | — | US | disclosed |
| US-20040092016-A1 | Enhanced homologous recombination mediated by lambda recombination proteins | THE GOVT. OF THE USA AS THE SECRETARY OF THE DEPT. OF HEALTH AND HUMAN SERVICES | 2004-05-13 | — | — | US | disclosed |
| US-20030224521-A1 | Enhanced homologous recombination mediated by lambda recombination proteins | THE GOV. OF THE USA SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-12-04 | — | — | US | disclosed |
| EP-1311661-A2 | ENHANCED HOMOLOGOUS RECOMBINATION MEDIATED BY LAMBDA RECOMBINATION PROTEINS | The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014495-A2 | ENHANCED HOMOLOGOUS RECOMBINATION MEDIATED BY LAMBDA RECOMBINATION PROTEINS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2002-02-21 | — | — | WO | disclosed |