Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3844244 | 0.93 | PDE2A (0.36) | RXFP1TP53PDE2APDE10ANPC1 | |
| SCHEMBL69222 | 0.77 | NPC1 (0.44) | TP53PDE2APDE10ANPC1CASP3 | |
| SCHEMBL29369509 | 0.77 | NPC1 (0.44) | TP53PDE2APDE10ANPC1CASP3 | |
| SCHEMBL2888290 | 0.75 | NPC1 (0.43) | TP53PDE2APDE10ANPC1CASP3 | |
| SCHEMBL3847246 | 0.74 | KMT2A (0.40) | PDE2APDE10ANPC1CASP3RAB9A | |
| SCHEMBL174777 | 0.73 | TP53 (0.43) | RXFP1TP53HTR1ADRD2DRD4 | |
| SCHEMBL3332556 | 0.72 | ALDH1A1 (0.34) | RXFP1TP53NPC1RAB9AL3MBTL1 | |
| SCHEMBL3851086 | 0.71 | KMT2A (0.38) | PDE2APDE10ANPC1CASP3RAB9A | |
| SCHEMBL68893 | 0.71 | NPC1 (0.47) | TP53PDE2APDE10ANPC1CASP3 | |
| SCHEMBL2348112 | 0.70 | NPC1 (0.41) | RXFP1PDE2APDE10ANPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042491-A1 | Pyridazines as fungicides | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |