SCHEMBL3852137

SCHEMBL3852137

O=C1NC(=O)c2c1c(Br)cc1ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 8/20 0.44
CCND1 P24385 8/20 0.44
CCNE2 O96020 6/20 0.44
CCNE1 P24864 6/20 0.44
CDK2 P24941 6/20 0.44
CCNB2 O95067 5/20 0.44
CDK1 P06493 5/20 0.44
CCNB1 P14635 5/20 0.44
CCNB3 Q8WWL7 5/20 0.44
CAMK2B Q13554 4/20 0.44
CAMK2G Q13555 4/20 0.44
CAMK2D Q13557 4/20 0.44
CAMK2A Q9UQM7 4/20 0.44
PRKACA P17612 2/20 0.44
PRKACG P22612 2/20 0.44
PRKACB P22694 2/20 0.44
CDK5 Q00535 4/20 0.41
CDK5R1 Q15078 4/20 0.41
CCNA2 P20248 2/20 0.41
CCNT1 O60563 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1889878 0.78 PARP1 (0.55) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL6848266 0.78 CDK4 (0.42) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL339346 0.78 GAA (0.41) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL1756365 0.78 TRPM4 (0.48) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL789452 0.76 TRPM4 (0.47) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL3967192 0.76 ALDH1A1 (0.40) MEN1KMT2AALDH1A1HIF1ACYP1B1
SCHEMBL856132 0.75 CDK4 (0.39) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL7767469 0.75 MEN1 (0.50) CDK4PRKCGPRKCBPRKCAMEN1
SCHEMBL9612596 0.74 CES1 (0.50) MEN1MAPTKMT2AALDH1A1HIF1A
SCHEMBL17045724 0.74 CLK1 (0.49) CDK4CCND1CCNE2CCNE1CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070270570-A1 WHITE ELECTROLUMINESCENT POLYMERIC MATERIAL AND PREPARATION THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINES ACADEMY OF SCIENCE (CN) 2007-11-22 US claimed
US-20050214568-A1 White electroluminescent polymeric material & preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE 2005-09-29 US claimed
US-7579091-B2 White electroluminescent polymeric material and preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2009-08-25 US disclosed
US-20070270570-A1 WHITE ELECTROLUMINESCENT POLYMERIC MATERIAL AND PREPARATION THEREOF CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINES ACADEMY OF SCIENCE (CN) 2007-11-22 US disclosed
US-20050214568-A1 White electroluminescent polymeric material & preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE 2005-09-29 US disclosed
US-3932413-A Process for the preparation of 4'-alkoxy-4-naphthalimido-pyrazolium compounds and intermediates therefor PRODUCTS CHIMIQUES UGINE KUHLMANN (FR) 1976-01-13 US disclosed