Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 5/20 | 0.39 |
| ▸ | CCND1 | P24385 | 5/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.38 |
| ▸ | PRKCG | P05129 | 2/20 | 0.38 |
| ▸ | PRKCB | P05771 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | PRKCA | P17252 | 2/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.38 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3852137 | 0.75 | CDK4 (0.44) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL6848266 | 0.75 | CDK4 (0.42) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL1756365 | 0.75 | TRPM4 (0.48) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL339346 | 0.75 | GAA (0.41) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL1889878 | 0.75 | PARP1 (0.55) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL789452 | 0.74 | TRPM4 (0.47) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL7767469 | 0.72 | MEN1 (0.50) | CDK4PRKCGPRKCBPRKCAMAPT | |
| SCHEMBL28173877 | 0.71 | MAPT (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6882828 | 0.71 | ALDH1A1 (0.39) | CDK4CCND1CDK5CDK5R1GSK3B | |
| SCHEMBL11667133 | 0.71 | CES1 (0.39) | CDK4CCND1CDK5CDK5R1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1445602-B1 | Fluorimetric Determination of an Analyte by an Intramolecular Quencher-Fluorophore-Conjugate | HOFFMANN LA ROCHE (CH) | 2012-03-28 | — | — | EP | claimed |
| US-7807402-B2 | Reagent for fluorimetric determination of analytes | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-10-05 | — | — | US | claimed |
| US-20080305469-A1 | Fluorimetric Determination of Analytes By An Intramolecular Quencher-Fluorophore Conjugate | ROCHE DIAGNOSTICS GMBH (DE) | 2008-12-11 | — | — | US | claimed |
| US-7378255-B2 | Fluorimetric determination of analytes by an intramolecular quencher-fluorophore conjugate | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2008-05-27 | — | — | US | claimed |
| US-20040234945-A1 | Fluorimetric determination of analytes by an intramolecular quencher-fluorophore conjugate | ROCHE DIAGNOSTICS GMBH (DE) | 2004-11-25 | — | — | US | claimed |
| EP-1445602-A1 | Fluorimetric Determination of an Analyte by an Intramolecular Quencher-Fluorophore-Conjugate | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-11 | — | — | EP | claimed |
| EP-1445602-B1 | Fluorimetric Determination of an Analyte by an Intramolecular Quencher-Fluorophore-Conjugate | HOFFMANN LA ROCHE (CH) | 2012-03-28 | — | — | EP | disclosed |
| US-7807402-B2 | Reagent for fluorimetric determination of analytes | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-20080305469-A1 | Fluorimetric Determination of Analytes By An Intramolecular Quencher-Fluorophore Conjugate | ROCHE DIAGNOSTICS GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| US-7378255-B2 | Fluorimetric determination of analytes by an intramolecular quencher-fluorophore conjugate | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2008-05-27 | — | — | US | disclosed |
| US-20040234945-A1 | Fluorimetric determination of analytes by an intramolecular quencher-fluorophore conjugate | ROCHE DIAGNOSTICS GMBH (DE) | 2004-11-25 | — | — | US | disclosed |
| EP-1445602-A1 | Fluorimetric Determination of an Analyte by an Intramolecular Quencher-Fluorophore-Conjugate | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-11 | — | — | EP | disclosed |