Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22242090 | 0.79 | RIPK1 (0.37) | HSD17B10RIPK1 | |
| SCHEMBL20600737 | 0.79 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL18876146 | 0.79 | HSD11B1 (0.35) | ALDH1A1RAB9ANPC1HSD11B1RIPK1 | |
| Ammonia Solution, Strong SCHEMBL28632131 | 0.78 | HSD11B1 (0.34) | ALDH1A1RAB9ANPC1HSD11B1ADORA3 | |
| SCHEMBL23408299 | 0.75 | RIPK1 (0.33) | RIPK1 | |
| SCHEMBL20666272 | 0.75 | RIPK1 (0.33) | RAB9ASMN1; SMN2NPC1RIPK1 | |
| SCHEMBL20674879 | 0.75 | NPC1 (0.33) | RAB9ASMN1; SMN2NPC1RIPK1MEN1 | |
| SCHEMBL24347829 | 0.75 | RIPK1 (0.33) | RIPK1KDM4E | |
| SCHEMBL20600798 | 0.75 | TTR (0.34) | RIPK1TTR | |
| SCHEMBL30798871 | 0.75 | GLRA3 (0.36) | ALDH1A1SMN1; SMN2NPC1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576098-B2 | Heterocyclic compounds as inhibitors of factor VIIa | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-18 | — | — | US | disclosed |
| EP-1828152-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FACTOR VIIA | BRISTOL MYERS SQUIBB CO (US) | 2008-08-20 | — | — | EP | disclosed |
| EP-1828152-A2 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FACTOR VIIA | Bristol-Myers Squibb Company (US) | 2007-09-05 | — | — | EP | disclosed |
| US-20060211720-A1 | Heterocyclic compounds as inhibitors of factor VIIa | BRISTOL-MYERS SQUIBB COMPANY | 2006-09-21 | — | — | US | disclosed |
| WO-2006062972-A2 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF FACTOR VIIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-06-15 | — | — | WO | disclosed |
| US-5888940-A | DESICCATING PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-30 | — | — | US | disclosed |
| CN-1194645-A | Substituted benzothiazols with herbicidal action | BASF AG (DE) | 1998-09-30 | — | — | CN | disclosed |
| EP-0862569-A1 | SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997008171-A1 | SUBSTITUTED BENZOTHIAZOLS WITH HERBICIDAL ACTION | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-06 | — | — | WO | disclosed |
| EP-0249009-B1 | MONOAZO COLORANTS | MITSUBISHI KASEI CORPORATION (JP) | 1991-07-03 | — | — | EP | disclosed |
| US-4960871-A | Fiber-reactive halotriazine pyridine-based monoazo colorant | MITSUBISHI CHEMICAL INDUSTRIES INC. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0385676-A1 | Biocidal compositions and treatments | Albright & Wilson Limited (GB) | 1990-09-05 | — | — | EP | disclosed |
| EP-0249009-A2 | Monoazo colorants | MITSUBISHI KASEI CORPORATION (JP) | 1987-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211720-A1 | Heterocyclic compounds as inhibitors of factor VIIa | TFPI, F7, HABP2 | ALDH1A1 3937/4885RAB9A 1180/4885HSD17B10 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.