SCHEMBL3852933

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3843699	0.89	DRD2 (0.46)	DRD2HTR1AHTR2AHTR7HTR6
	SCHEMBL3848099	0.88	DRD2 (0.59)	DRD2HTR1AHTR2AHTR7HTR6
	SCHEMBL3846117	0.88	DRD2 (0.52)	DRD2HTR1AHTR2AHTR7HTR6
	SCHEMBL3851411	0.88	DRD2 (0.58)	DRD2DRD3
	SCHEMBL3843977	0.87	POLB (0.60)	DRD2HTR1AHTR2AHTR7HTR6
	SCHEMBL3843679	0.87	DRD2 (0.51)	DRD2HTR1AHTR7DRD3POLB
	SCHEMBL3851253	0.86	DRD2 (0.52)	DRD2HTR1AHTR2AHTR7HTR6
	SCHEMBL4490509	0.86	POLB (0.52)	DRD2HTR1AHTR2AHTR7HTR6
	SCHEMBL3844112	0.86	DRD2 (0.51)	DRD2HTR1ADRD3POLB
	SCHEMBL3844241	0.86	DRD2 (0.55)	DRD2DRD3CYP1A2CYP2D6ADAMTS5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.