Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3855788 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL3858614 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL15027046 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL4626237 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL3848890 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL3854311 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL3860072 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL4624432 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL3853141 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 | |
| SCHEMBL3858118 | 1.00 | DGKA (0.61) | DGKAMAPTDNM1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1380293-A9 | BONE METABOLISM IMPROVING AGENTS | The Nisshin OilliO Group, Ltd. (JP) | 2009-09-23 | — | — | EP | disclosed |
| US-7579374-B2 | Agent for improving bone metabolism | THE NISSHIN OILLIO GROUP, LTD. (JP) | 2009-08-25 | — | — | US | disclosed |
| US-20040058995-A1 | Agent for improving bone metabolism | THE NISSHIN OILLIO, LTD. | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058995-A1 | Agent for improving bone metabolism | FABP2, FABP4, SREBF2 | DGKA 301/4885MAPT 4864/4885DNM1 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.