SCHEMBL3853181

SCHEMBL3853181

O=C(O)c1ccc(C(=O)O)c(CC2CCCCC2)c1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 3/20 0.51
KDM5B Q9UGL1 2/20 0.45
KDM5A P29375 1/20 0.45
KMT2A Q03164 2/20 0.44
KMO O15229 1/20 0.44
HSD17B10 Q99714 1/20 0.43
GAA P10253 1/20 0.43
SRD5A2 P31213 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
RARB P10826 1/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446092 0.98 PPM1D (0.49) PPM1DKDM5BKDM5AKMT2AKMO
SCHEMBL27741282 0.89 PPM1D (0.50) PPM1DKDM5BKDM5AKMT2AKMO
SCHEMBL28048040 0.87 PPM1D (0.48) PPM1DKDM5BKDM5AKMT2AKMO
SCHEMBL2361733 0.84 PPM1D (0.52) PPM1DKMT2AKMOHSD17B10GAA
SCHEMBL28105519 0.84 PPM1D (0.45) PPM1DKDM5BKDM5AKMT2AKMO
SCHEMBL2426837 0.83 PPM1D (0.41) PPM1DKMT2AGAAKDM4E
SCHEMBL28175940 0.81 PARP10 (0.49) PPM1D
SCHEMBL28047118 0.80 KDM4E (0.42) PPM1DKMT2AGAAKDM4E
SCHEMBL7298560 0.80 PPM1D (0.53) PPM1DKDM5BKDM5AKMT2A
SCHEMBL31319118 0.79 PPM1D (0.49) PPM1DKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1697772-A1 OPTICAL STRUCTURES Reflexite Corporation (US) 2006-09-06 EP claimed
WO-2005057257-A1 OPTICAL STRUCTURES REFLEXITE CORPORATION (US) 2005-06-23 WO claimed
US-20040169928-A1 Optical structures REFLEXITE CORPORATION 2004-09-02 US claimed
EP-1697772-B9 METHOD AND APPARATUS FOR FORMING AN OPTICAL STRUCTURE REFLEXITE CORP (US) 2009-09-23 EP disclosed
EP-1697772-B1 METHOD AND APPARATUS FOR FORMING AN OPTICAL STRUCTURE REFLEXITE CORP (US) 2009-04-15 EP disclosed
US-7364314-B2 Optical structures REFLEXITE CORPORATION (US) 2008-04-29 US disclosed
EP-1697772-A1 OPTICAL STRUCTURES Reflexite Corporation (US) 2006-09-06 EP disclosed
WO-2005057257-A1 OPTICAL STRUCTURES REFLEXITE CORPORATION (US) 2005-06-23 WO disclosed
US-20040169928-A1 Optical structures REFLEXITE CORPORATION 2004-09-02 US disclosed