SCHEMBL3853871

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3849149	0.90	DRD2 (0.49)	DRD2DRD3HTTMAPTHTR1A
	SCHEMBL13630498	0.89	USP2 (0.52)	POLBDRD2DRD3HTTUSP2
	SCHEMBL3844984	0.87	ALDH1A1 (0.56)	POLBMAPK1DRD2DRD3HTT
	SCHEMBL3851245	0.85	ALDH1A1 (0.55)	POLBDRD2DRD3HTTUSP2
	SCHEMBL3851512	0.85	DRD2 (0.47)	DRD2DRD3HTTHTR1AALDH1A1
	SCHEMBL3844066	0.83	DRD2 (0.59)	DRD2DRD3MAPTHTR1AALDH1A1
	SCHEMBL3863328	0.82	DRD2 (0.57)	DRD2DRD3LMNAMAPT
	SCHEMBL3843651	0.81	DRD4 (0.47)	DRD2DRD3LMNAMAPTHTR1A
	SCHEMBL3847671	0.80	DRD2 (0.59)	DRD2DRD3HTR1AALDH1A1KMT2A
	SCHEMBL17226518	0.80	HSD17B10 (0.48)	POLBMAPK1DRD2DRD3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.