Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 16/20 | 0.52 |
| ▸ | IKBKB | O14920 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14145116 | 0.80 | ATM (0.63) | FYN | |
| SCHEMBL14145500 | 0.78 | IKBKB (0.43) | FYNIKBKBRAD52 | |
| SCHEMBL13874171 | 0.78 | IKBKB (0.43) | FYNIKBKB | |
| SCHEMBL3846712 | 0.78 | MKNK1 (0.61) | FYN | |
| SCHEMBL3846791 | 0.78 | MAPK8 (0.45) | FYNIKBKBRAD52 | |
| SCHEMBL3847512 | 0.77 | MKNK1 (0.51) | FYN | |
| SCHEMBL3850100 | 0.76 | PIK3CA (0.53) | FYN | |
| SCHEMBL13874025 | 0.76 | PIK3CA (0.44) | FYN | |
| SCHEMBL3848924 | 0.73 | FYN (0.41) | FYNIKBKBRAD52 | |
| SCHEMBL19466887 | 0.73 | IKBKB (0.68) | FYNIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048142-A2 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | Eisai R&D Management Co., Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |
| EP-1382603-B1 | NITROGENOUS FUSED-RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | EISAI R&D MAN CO LTD (JP) | 2008-07-23 | — | — | EP | disclosed |
| US-7074801-B1 | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof | EISAI CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1382603-A1 | NITROGENOUS FUSED−RING COMPOUND HAVING PYRAZOLYL GROUP AS SUBSTITUENT AND MEDICINAL COMPOSITION THEREOF | Eisai Co., Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |