Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3730313 | 0.86 | MAPT (0.45) | IDO1GAAPTGER1MEN1KMT2A | |
| SCHEMBL21987969 | 0.82 | IDO1 (0.48) | IDO1GAAKDM4AALDH1A1HPGD | |
| SCHEMBL7404611 | 0.82 | IDO1 (0.41) | IDO1GAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7372767 | 0.81 | MAPT (0.58) | IDO1PTGER1CYP2C9MAPTNPSR1 | |
| SCHEMBL6921464 | 0.81 | IDO1 (0.50) | IDO1GAAPTGER1KDM4AALDH1A1 | |
| SCHEMBL27988801 | 0.81 | IDO1 (0.53) | IDO1GAAKDM4AALDH1A1HPGD | |
| SCHEMBL711731 | 0.81 | IDO1 (0.50) | IDO1GAAKDM4AALDH1A1HPGD | |
| SCHEMBL700928 | 0.81 | IDO1 (0.50) | IDO1GAAKDM4AALDH1A1HPGD | |
| SCHEMBL7257883 | 0.81 | IDO1 (0.46) | IDO1GAAPTGER1KDM4AALDH1A1 | |
| SCHEMBL3734185 | 0.80 | ANO1 (0.51) | IDO1GAAKDM4AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131245-A1 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-29 | — | — | WO | disclosed |