SCHEMBL38556

SCHEMBL38556

C[C@H](N)C(=O)OC1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.50
EPHX1 P07099 2/20 0.44
NAAA Q02083 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
HTT P42858 1/20 0.40
CYP2C19 P33261 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
GAA P10253 1/20 0.36
FABP7 O15540 1/20 0.36
FABP5 Q01469 1/20 0.36
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
STS P08842 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16554168 1.00 CYP19A1 (0.50) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL16373577 1.00 CYP19A1 (0.50) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL8131133 1.00 CYP19A1 (0.50) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL18630281 1.00 CYP19A1 (0.50) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL770738 1.00 CYP19A1 (0.50) CYP19A1EPHX1NAAAL3MBTL1HTT
SCHEMBL16554167 1.00 CYP19A1 (0.50) CYP19A1EPHX1NAAAL3MBTL1HTT
Hydrochloric Acid SCHEMBL28986488 0.98 CYP19A1 (0.49) CYP19A1EPHX1NAAAL3MBTL1HTT
Hydrochloric Acid SCHEMBL28854937 0.98 CYP19A1 (0.49) CYP19A1EPHX1NAAAL3MBTL1HTT
Hydrochloric Acid SCHEMBL28854935 0.98 CYP19A1 (0.49) CYP19A1EPHX1NAAAL3MBTL1HTT
Hydrochloric Acid SCHEMBL18492053 0.98 CYP19A1 (0.49) CYP19A1EPHX1NAAAL3MBTL1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170269-A1 NANOPARTICLES FOR DIRECT REGULATION OF MITOCHONDRIAL GENE EXPRESSION RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-05-29 US claimed
WO-2024101935-A1 AMPHIPHILIC CONJUGATE COMPRISING SELF-ASSEMBLIYABLE PEPTIDE MOLECULE AND USE THEREOF 울산과학기술원 2024-05-16 WO claimed
US-20240092849-A1 SELECTIVE MCL-1 BINDING PEPTIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2024-03-21 US claimed
US-20240009331-A1 UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR TARGETED RADIOLABELED PEPTIDE CONJUGATES CURASIGHT A/S (DK) 2024-01-11 US claimed
US-20230381327-A1 REACTIVE CONJUGATES DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2023-11-30 US claimed
EP-4255506-A1 UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR TARGETED RADIOLABELED PEPTIDE CONJUGATES Curasight A/S (DK) 2023-10-11 EP claimed
EP-3013340-B9 SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF JANSSEN PHARMACEUTICALS INC (US) 2023-10-04 EP claimed
EP-4225378-A1 REACTIVE CONJUGATES Debiopharm Research & Manufacturing S.A. (CH) 2023-08-16 EP claimed
EP-3013340-B1 SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF JANSSEN BIOPHARMA INC (US) 2023-06-07 EP claimed
WO-2023019333-A1 MACROCYCLIC MIMETIC ANTAGONISTS WITH BIOLOGICAL ACTIVITY, USES THEREOF AND COMPOSITIONS NOVAGEIA BIOTECNOLOGIA LTDA (BR) 2023-02-23 WO claimed
EP-1017713-A4 CYCLIC AGONISTS AND ANTAGONISTS OF C5a RECEPTORS AND G PROTEIN-COUPLED RECEPTORS UNIV QUEENSLAND (AU) 2002-07-24 EP claimed
CN-1353701-A Peptidyl heterocyclic ketones useful as tryptase inhibitors ORTHO MCNEIL PHARM INC (US) 2002-06-12 CN claimed
EP-1017713-A1 CYCLIC AGONISTS AND ANTAGONISTS OF C5a RECEPTORS AND G PROTEIN-COUPLED RECEPTORS THE UNIVERSITY OF QUEENSLAND (AU) 2000-07-12 EP claimed
EP-0961779-A1 SUBSTITUTED AMINO BICYCLIC-$g(b)-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS SYNPHAR LABORATORIES INC. (CA) 1999-12-08 EP claimed
WO-1999000406-A1 CYCLIC AGONISTS AND ANTAGONISTS OF C5a RECEPTORS AND G PROTEIN-COUPLED RECEPTORS THE UNIVERSITY OF QUEENSLAND (AU) 1999-01-07 WO claimed
WO-1998032766-A1 SUBSTITUTED AMINO BICYCLIC-β-LACTAM PENAM AND CEPHAM DERIVATIVES AS CYSTEINE PROTEASE INHIBITORS SYNPHAR LABORATORIES INC. (US) 1998-07-30 WO claimed
CN-1156964-A Novel Peptides MERCK & CO INC (US) 1997-08-13 CN claimed
WO-1997010222-A1 METHOD FOR PREPARING PIPERAZINES CORTECH, INC. (US) 1997-03-20 WO claimed
CN-1112125-A Acyloxyhexanoic acid derivatives CIBA GEIGY AG (CH) 1995-11-22 CN claimed
EP-0652893-A1 KININOGENASE INHIBITORS SZELKE, Michael (GB) 1995-05-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092849-A1 SELECTIVE MCL-1 BINDING PEPTIDES MCL1, BCL2L11, BCL2L1 CYP19A1 4830/4885EPHX1 4709/4885NAAA 4415/4885
US-20230381327-A1 REACTIVE CONJUGATES FCGR3B, FCGR1A, FCGR2A CYP19A1 3539/4885EPHX1 4230/4885NAAA 1468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.