Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 6/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL384958 | 1.00 | S1PR1 (0.56) | S1PR1S1PR3S1PR5DPP4ACHE | |
| Hydrochloric Acid SCHEMBL386151 | 0.99 | S1PR1 (0.56) | S1PR1S1PR3S1PR5DPP4ACHE | |
| Hydrochloric Acid SCHEMBL387256 | 0.99 | S1PR1 (0.56) | S1PR1S1PR3S1PR5DPP4ACHE | |
| SCHEMBL12743984 | 0.97 | S1PR1 (0.60) | S1PR1S1PR3S1PR5DPP4ACHE | |
| SCHEMBL383826 | 0.97 | S1PR1 (0.60) | S1PR1S1PR3S1PR5DPP4ACHE | |
| Hydrochloric Acid SCHEMBL388133 | 0.96 | S1PR1 (0.59) | S1PR1S1PR3S1PR5DPP4ACHE | |
| SCHEMBL27599915 | 0.91 | S1PR1 (0.59) | S1PR1S1PR3S1PR5DPP4ACHE | |
| Hydrochloric Acid SCHEMBL384022 | 0.91 | S1PR1 (0.51) | S1PR1S1PR3S1PR5MAPTRXFP1 | |
| SCHEMBL3511310 | 0.90 | S1PR1 (0.69) | S1PR1S1PR3S1PR5 | |
| SCHEMBL3510888 | 0.90 | S1PR1 (0.69) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081702-A1 | PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS OR TREATMENT OF HEPATITIS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-04-01 | — | — | US | claimed |
| EP-2149549-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF HEPATITIS | Daiichi Sankyo Company, Limited (JP) | 2010-02-03 | — | — | EP | claimed |
| EP-2045325-B1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO CO LTD (JP) | 2012-09-19 | — | — | EP | disclosed |
| EP-1915994-B1 | CYCLIC AMINE DERIVATIVES IN COMBINATION WITH PPAR REGULATORS | DAIICHI SANKYO CO LTD (JP) | 2012-08-01 | — | — | EP | disclosed |
| US-8101650-B2 | Method for treating a immunology-related disease | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-8067396-B2 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2011-11-29 | — | — | US | disclosed |
| US-20100248227-A1 | DRUG-PHOSPHORYLATING ENZYME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100081702-A1 | PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS OR TREATMENT OF HEPATITIS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-04-01 | — | — | US | disclosed |
| US-20100081702-A1 | PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS OR TREATMENT OF HEPATITIS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-04-01 | — | — | US | disclosed |
| US-20100081702-A1 | PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS OR TREATMENT OF HEPATITIS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-04-01 | — | — | US | disclosed |
| US-20100035842-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2045325-A1 | DRUG-PHOSPHORYLATING ENZYME | Daiichi Sankyo Company, Limited (JP) | 2009-04-08 | — | — | EP | disclosed |
| US-20080153882-A1 | Pharmaceutical Composition Comprising Ppar Regulator | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-06-26 | — | — | US | disclosed |
| US-20080153882-A1 | Pharmaceutical Composition Comprising Ppar Regulator | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-06-26 | — | — | US | disclosed |
| EP-1915994-A1 | CYCLIC AMINE DERIVATIVE CONTAINING PPAR REGULATOR | Sankyo Company, Limited (JP) | 2008-04-30 | — | — | EP | disclosed |
| US-20070142335-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | SANKYO COMPANY, LIMITED (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070105933-A1 | Amino alcohol compounds | SANKYO COMPANY, LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| US-7199150-B2 | Amino alcohol compounds | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20050043386-A1 | Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these | SANKYO COMPANY, LIMITED (JP) | 2005-02-24 | — | — | US | disclosed |
| EP-1471054-A1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | Sankyo Company, Limited (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043386-A1 | Amino alcohol derivatives or phosphonic acid derivatives and pharmaceutical compositions containing these | PHOSPHO1, CD4, FCGRT | S1PR1 257/4885S1PR3 414/4885S1PR5 503/4885 |
| US-20080153882-A1 | Pharmaceutical Composition Comprising Ppar Regulator | PPARG, PPARA, PPARD | S1PR1 282/4885S1PR3 281/4885S1PR5 725/4885 |
| US-20100081702-A1 | PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS OR TREATMENT OF HEPATITIS | SLC10A1, C1S, C1R | S1PR1 516/4885S1PR3 376/4885S1PR5 1153/4885 |
| US-20070105933-A1 | Amino alcohol compounds | ADH1C, C9, SSB | S1PR1 465/4885S1PR3 504/4885S1PR5 1007/4885 |
| US-20070142335-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | HRH3, C3AR1, HRH4 | S1PR1 70/4885S1PR3 89/4885S1PR5 163/4885 |
| US-20100035842-A1 | Amino alcohol compounds or phosphonic acid derivatives thereof | PHOSPHO1, ADH1C, ADH1A | S1PR1 593/4885S1PR3 622/4885S1PR5 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.