Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3852110 | 0.88 | VDR (0.37) | VDRPPARDRAB9A | |
| SCHEMBL3855835 | 0.85 | VDR (0.50) | VDRPPARD | |
| SCHEMBL13714180 | 0.79 | VDR (0.52) | VDR | |
| SCHEMBL13713993 | 0.78 | VDR (0.50) | VDRPPARD | |
| SCHEMBL13714020 | 0.77 | VDR (0.59) | VDR | |
| SCHEMBL13714045 | 0.74 | VDR (0.51) | VDRPPARD | |
| SCHEMBL13713954 | 0.73 | VDR (0.60) | VDR | |
| SCHEMBL3851531 | 0.73 | VDR (0.60) | VDR | |
| SCHEMBL3855199 | 0.72 | VDR (0.47) | VDR | |
| SCHEMBL13713992 | 0.70 | VDR (0.42) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579488-B2 | Vitamin D receptor modulators | ELI LILLY AND COMPANY (US) | 2009-08-25 | — | — | US | disclosed |
| US-20070106095-A1 | Vitamin d receptor modulators | ELI LILLY AND COMPANY | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070106095-A1 | Vitamin d receptor modulators | VDR, CYP2R1, CYP24A1 | VDR 1/4885PPARD 19/4885ADAM17 1553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.