SCHEMBL3856462

SCHEMBL3856462

C=CCSc1n[c]ncn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.41
TP53 P04637 3/20 0.40
HPGD P15428 4/20 0.34
RAB9A P51151 4/20 0.34
MAPT P10636 3/20 0.33
MEN1 O00255 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C19 P33261 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 2/20 0.33
CYP2D6 P10635 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GAA P10253 2/20 0.32
LMNA P02545 2/20 0.32
MAPK1 P28482 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950950 0.74 L3MBTL1 (0.52) L3MBTL1TP53HPGDRAB9AMAPT
SCHEMBL15546478 0.71
SCHEMBL692444 0.67 L3MBTL1 (0.58) L3MBTL1TP53HPGDRAB9AMEN1
SCHEMBL1476980 0.67 HPGD (0.34) L3MBTL1TP53HPGDRAB9AMAPT
SCHEMBL9279974 0.67 GAA (0.43) L3MBTL1TP53HPGDRAB9AMAPT
SCHEMBL5865469 0.67 TP53 (0.50) L3MBTL1TP53HPGDRAB9AMAPT
SCHEMBL369459 0.66 KMT2A (0.44) L3MBTL1TP53HPGDRAB9AMAPT
SCHEMBL13085024 0.65 NPSR1 (0.46) L3MBTL1TP53HPGDRAB9AMAPT
SCHEMBL8074603 0.64 TP53 (0.44) L3MBTL1TP53HPGDRAB9AMAPT
SCHEMBL8138105 0.64 MAPT (0.37) L3MBTL1HPGDRAB9AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 US claimed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 US claimed
EP-1887046-A2 Reactive dyes containing an alkylthio-s-triazinyl reactive group Everlight USA, Inc. (US) 2008-02-13 EP claimed
EP-1887046-A3 Reactive dyes containing an alkylthio-s-triazinyl reactive group Everlight USA, Inc. (US) 2009-11-04 EP disclosed
EP-1887046-A3 Reactive dyes containing an alkylthio-s-triazinyl reactive group Everlight USA, Inc. (US) 2009-11-04 EP disclosed
US-7439340-B2 For exhaust dyeing, cold batch-up dyeing and continuous dyeing EVERLIGHT USA, INC. (US) 2008-10-21 US disclosed
US-7439340-B2 For exhaust dyeing, cold batch-up dyeing and continuous dyeing EVERLIGHT USA, INC. (US) 2008-10-21 US disclosed
US-7439340-B2 For exhaust dyeing, cold batch-up dyeing and continuous dyeing EVERLIGHT USA, INC. (US) 2008-10-21 US disclosed
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 US disclosed
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 US disclosed
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 US disclosed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 US disclosed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 US disclosed
US-20080039614-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-02-14 US disclosed
EP-1887046-A2 Reactive dyes containing an alkylthio-s-triazinyl reactive group Everlight USA, Inc. (US) 2008-02-13 EP disclosed
EP-1887046-A2 Reactive dyes containing an alkylthio-s-triazinyl reactive group Everlight USA, Inc. (US) 2008-02-13 EP disclosed
EP-1887046-A2 Reactive dyes containing an alkylthio-s-triazinyl reactive group Everlight USA, Inc. (US) 2008-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group TST, IK, NOX5 L3MBTL1 3414/4885TP53 2029/4885HPGD 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.