Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 1.00 |
| ▸ | STAT3 | P40763 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | APP | P05067 | 11/20 | 0.82 |
| ▸ | MAPT | P10636 | 10/20 | 0.82 |
| ▸ | BACE1 | P56817 | 5/20 | 0.82 |
| ▸ | MMP9 | P14780 | 4/20 | 0.82 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.82 |
| ▸ | TSHR | P16473 | 2/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.82 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.82 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.82 |
| ▸ | MAOA | P21397 | 2/20 | 0.82 |
| ▸ | MAOB | P27338 | 2/20 | 0.82 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.82 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.82 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856831 | 1.00 | NFKB1 (1.00) | NFKB1ALOX5STAT3NFKB2RELA | |
| Curcumin SCHEMBL27852357 | 0.92 | APP (0.97) | NFKB1ALOX5STAT3NFKB2RELA | |
| SCHEMBL3855700 | 0.91 | NFKB1 (0.84) | NFKB1ALOX5STAT3NFKB2RELA | |
| SCHEMBL3855939 | 0.91 | NFKB1 (0.84) | NFKB1ALOX5STAT3NFKB2RELA | |
| SCHEMBL3855986 | 0.91 | NFKB1 (0.84) | NFKB1ALOX5STAT3NFKB2RELA | |
| SCHEMBL3855933 | 0.91 | NFKB1 (0.84) | NFKB1ALOX5STAT3NFKB2RELA | |
| SCHEMBL3855982 | 0.91 | NFKB1 (0.84) | NFKB1ALOX5STAT3NFKB2RELA | |
| SCHEMBL3855697 | 0.91 | NFKB1 (0.84) | NFKB1ALOX5STAT3NFKB2RELA | |
| SCHEMBL3861948 | 0.91 | NFKB1 (0.82) | NFKB1ALOX5STAT3NFKB2RELA | |
| SCHEMBL3861950 | 0.91 | NFKB1 (0.82) | NFKB1ALOX5STAT3NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589123-B2 | Chemical compounds | PHYTOPHARM PLC (GB) | 2009-09-15 | — | — | US | claimed |
| US-7589123-B2 | Chemical compounds | PHYTOPHARM PLC (GB) | 2009-09-15 | — | — | US | disclosed |
| CN-101511350-A | Dioxo-alkanes and dioxo-alkenes | PHYTOPHARM PLC (GB) | 2009-08-19 | — | — | CN | disclosed |
| EP-2046311-A2 | DIOXO-ALKANES AND DIOXO-ALKENES | Phytopharm Plc (GB) | 2009-04-15 | — | — | EP | disclosed |
| US-20080045591-A1 | Chemical Compounds | VECTURA LIMITED (GB) | 2008-02-21 | — | — | US | disclosed |
| WO-2008003978-A2 | DIOXO-ALKANES AND DIOXO-ALKENES | PHYTOPHARM PLC (GB) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045591-A1 | Chemical Compounds | CYP11B1, CYP11B2, CYP2S1 | NFKB1 1509/4885ALOX5 1556/4885STAT3 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.