Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.65 |
| ▸ | CA1 | P00915 | 3/20 | 0.65 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151185 | 1.00 | CA2 (0.65) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL3452084 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL7209672 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL276768 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL7212250 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL490747 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL3855790 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL3861238 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL1672036 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 | |
| SCHEMBL7204823 | 0.98 | CA2 (0.63) | CA2CA1GRIK1GRIK2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589221-B2 | Industrial scale process; treats neurodegenerative diseases; high optical purity; less dangerous reaction | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |
| US-20060135802-A1 | Process for producing (2r)-2-propyloctanoic acid and intermediate therefor | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135802-A1 | Process for producing (2r)-2-propyloctanoic acid and intermediate therefor | CYP51A1, POR, GRHPR | CA2 723/4885CA1 737/4885GRIK1 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.