SCHEMBL3857048

SCHEMBL3857048

NN(C(=O)O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.51
FABP5 Q01469 3/20 0.50
FABP7 O15540 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
EPHX2 P34913 1/20 0.45
HTR2A P28223 1/20 0.41
CASP3 P42574 2/20 0.40
MDM4 O15151 1/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29403341 0.84 KMT2A (0.50) KMT2AFABP5FABP7CA1CA2
SCHEMBL4214086 0.83 KMT2A (0.52) KMT2AFABP5FABP7CA1CA2
SCHEMBL9170700 0.82 KMT2A (0.46) KMT2AFABP5FABP7CA1CA2
SCHEMBL26931389 0.82 KMT2A (0.46) KMT2AFABP5FABP7CA1CA2
SCHEMBL120280 0.82 FABP5 (0.50) KMT2AFABP5FABP7CA1CA2
SCHEMBL5969982 0.81 FABP5 (0.49) KMT2AFABP5FABP7CA1CA2
SCHEMBL10037319 0.80 KMT2A (0.51) KMT2AFABP5FABP7CA1CA2
SCHEMBL30584150 0.80 KMT2A (0.51) KMT2AFABP5FABP7CA1CA2
SCHEMBL119279 0.79 FABP5 (0.48) KMT2AFABP5FABP7CA1CA2
SCHEMBL119531 0.79 FABP5 (0.48) KMT2AFABP5FABP7CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9125880-B2 Polymer conjugates of interferon-beta with enhanced biological potency MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2015-09-08 US disclosed
EP-1667708-B9 POLYETHYLENE GLYCOL CONJUGATES OF INTERFERON-BETA-1b WITH ENHANCED IN VITRO BIOLOGICAL POTENCY MOUNTAIN VIEW PHARMACEUTICALS (US) 2012-10-31 EP disclosed
EP-1667708-B1 POLYETHYLENE GLYCOL CONJUGATES OF INTERFERON-BETA-1b WITH ENHANCED IN VITRO BIOLOGICAL POTENCY MOUNTAIN VIEW PHARMACEUTICALS (US) 2012-06-06 EP disclosed
US-20090105091-A1 Modified Amino Acids TECHNISCHE UNIVERSITAT WIEN (AT) 2009-04-23 US disclosed
EP-1667708-A4 POLYMER CONJUGATES OF INTERFERON- BETA WITH ENHANCED BIOLOGICAL POTENCY MOUNTAIN VIEW PHARMACEUTICALS (US) 2009-01-14 EP disclosed
EP-1989180-A1 MODIFIED AMINO ACIDS Technische Universität Wien (AT) 2008-11-12 EP disclosed
WO-2007095980-A1 MODIFIED AMINO ACIDS TECHNISCHE UNIVERSITÄT WIEN (AT) 2007-08-30 WO disclosed
EP-1826199-A1 Modified amino acids Technische Universität Wien (AT) 2007-08-29 EP disclosed
EP-1667708-A2 POLYMER CONJUGATES OF INTERFERON- BETA WITH ENHANCED BIOLOGICAL POTENCY Mountain View Pharmaceuticals, Inc. (US) 2006-06-14 EP disclosed
WO-2004060299-A2 POLYMER CONJUGATES OF INTERFERON-BETA WITH ENHANCED BIOLOGICAL POTENCY MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2004-07-22 WO disclosed
US-20040126361-A1 Diagnosis, therapy multiple sclerosis; anticancer agents; central nervous system disorders; autoimmune diseases MOUNTAIN VIEW PHARMACEUTICALS, INC. 2004-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105091-A1 Modified Amino Acids SLC1A2, NR1H4, OXGR1 KMT2A 1541/4885FABP5 740/4885FABP7 575/4885
US-20040126361-A1 Diagnosis, therapy multiple sclerosis; anticancer agents; central nervous system disorders; autoimmune diseases IFNAR1, IFNG, CD40 KMT2A 3980/4885FABP5 1515/4885FABP7 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.