Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3861951 | 0.81 | ASAH2 (0.46) | MEN1KMT2AASAH1CYP2D6CYP1A2 | |
| SCHEMBL3859437 | 0.80 | MEN1 (0.48) | MEN1KMT2AASAH1SPHK1CYP2D6 | |
| Hydrochloric Acid SCHEMBL3857420 | 0.79 | MEN1 (0.47) | MEN1KMT2AASAH1SPHK1CYP2D6 | |
| SCHEMBL4860226 | 0.79 | TLR8 (0.44) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL3865356 | 0.79 | ASAH1 (0.44) | MEN1KMT2AASAH1SPHK1CYP2D6 | |
| SCHEMBL4862013 | 0.78 | SIGMAR1 (0.41) | MEN1KMT2ACYP1A2MAPTLMNA | |
| SCHEMBL4854597 | 0.77 | SIGMAR1 (0.38) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL4860025 | 0.75 | TLR7 (0.40) | CYP1A2MAPTCYP2C9CYP2C19SIGMAR1 | |
| SCHEMBL4860836 | 0.72 | FYN (0.44) | MEN1KMT2ACYP1A2MAPTPOLB | |
| Hydrochloric Acid SCHEMBL3859541 | 0.71 | MAPT (0.43) | MEN1KMT2ACYP1A2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | claimed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-7591860-B2 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL, S.A. (FR) | 2009-09-22 | — | — | US | disclosed |
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-02-09 | — | — | US | disclosed |
| EP-1580184-A1 | secondary N-alkylepolyhydroxilated p-phenylendiamines, dye composition comprising them, processes and uses | L'OREAL (FR) | 2005-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026777-A1 | N-alkylpolyhydroxylated secondary para-phenylenediamines, dye compositions comprising them, processes, and uses thereof | KRT18, CDC73, DSP | MEN1 4021/4885KMT2A 1656/4885ASAH1 2638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.