Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197121 | 0.68 | NOTUM (0.43) | NOTUM | |
| SCHEMBL1196467 | 0.67 | NOTUM (0.46) | NOTUM | |
| SCHEMBL1921376 | 0.63 | NOTUM (0.40) | NOTUM | |
| SCHEMBL1197255 | 0.59 | NOTUM (0.42) | NOTUM | |
| SCHEMBL23473967 | 0.59 | RAB9A (0.50) | NOTUM | |
| SCHEMBL1196334 | 0.57 | NOTUM (0.39) | NOTUM | |
| SCHEMBL5536423 | 0.56 | NOTUM (0.46) | NOTUM | |
| SCHEMBL15337360 | 0.56 | NOTUM (0.43) | NOTUM | |
| SCHEMBL14243389 | 0.56 | KMT2A (0.58) | NOTUM | |
| SCHEMBL17514541 | 0.55 | RAPGEF4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102189-A2 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | Brystol-Myers Squibb Company (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008076805-A2 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-26 | — | — | WO | disclosed |