Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 12/20 | 0.58 |
| ▸ | MAOB | P27338 | 12/20 | 0.58 |
| ▸ | F12 | P00748 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATR | Q13535 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16384134 | 0.81 | MAOA (0.68) | MAOAMAOBF12MAPK1 | |
| SCHEMBL2885719 | 0.81 | ATR (0.55) | ATR | |
| SCHEMBL2885651 | 0.81 | ATR (0.57) | ATR | |
| SCHEMBL2889859 | 0.77 | IKBKB (0.54) | ATR | |
| SCHEMBL2890336 | 0.77 | ATR (0.55) | ATR | |
| SCHEMBL2889406 | 0.76 | MCHR1 (0.73) | ATR | |
| SCHEMBL11462954 | 0.76 | MAOB (0.91) | MAOAMAOBF12MAPK1 | |
| SCHEMBL2890112 | 0.76 | ATR (0.56) | MAPK1ATR | |
| SCHEMBL4389144 | 0.74 | MAOA (1.00) | MAOAMAOBF12MAPK1 | |
| SCHEMBL2888136 | 0.74 | CHRNA7 (0.54) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027086-A2 | N-BENZOYL-AND N-BENZYLPYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS | Wyeth (US) | 2009-02-25 | — | — | EP | claimed |
| WO-2007136668-A2 | N-BENZOYL-AND N-BENZYLPYRROLIDIN-3-YLAMINES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2007-11-29 | — | — | WO | claimed |