SCHEMBL3858701

SCHEMBL3858701

CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2Cl)(C(=O)N2CCOCC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SLC6A9 P48067 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3850161 0.89 SLC6A9 (1.00) SLC6A9
SCHEMBL13714025 0.83 SLC6A9 (0.90) SLC6A9
SCHEMBL3848851 0.80 SLC6A9 (0.71) SLC6A9
SCHEMBL3848705 0.80 SLC6A9 (0.90) SLC6A9
SCHEMBL1689569 0.79 SLC6A9 (0.75) SLC6A9
SCHEMBL5584896 0.76 SLC6A9 (0.70) SLC6A9
SCHEMBL14836494 0.76 SLC6A9 (0.70) SLC6A9
SCHEMBL3853282 0.76 SLC6A9 (0.77) SLC6A9
SCHEMBL3848872 0.76 SLC6A9 (0.61) SLC6A9
SCHEMBL14836692 0.76 SLC6A9 (0.80) SLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576083-B2 Morpholinyl piperidine glycine transporter inhibitors MERCK & CO., INC. (US) 2009-08-18 — — US disclosed
US-7576083-B2 Morpholinyl piperidine glycine transporter inhibitors MERCK & CO., INC. (US) 2009-08-18 — — US disclosed
US-7576083-B2 Morpholinyl piperidine glycine transporter inhibitors MERCK & CO., INC. (US) 2009-08-18 — — US disclosed
US-20070249606-A1 Morpholinyl Piperidine Glycine Transporter Inhibitors MERCK SHARP & DOHME CORP. 2007-10-25 — — US disclosed
US-20070249606-A1 Morpholinyl Piperidine Glycine Transporter Inhibitors MERCK SHARP & DOHME CORP. 2007-10-25 — — US disclosed
US-20070249606-A1 Morpholinyl Piperidine Glycine Transporter Inhibitors MERCK SHARP & DOHME CORP. 2007-10-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249606-A1 Morpholinyl Piperidine Glycine Transporter Inhibitors SLC1A1, SLC1A2, SLC6A7 SLC6A9 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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