⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652011 | 0.80 | — | — | |
| SCHEMBL244256 | 0.79 | — | — | |
| SCHEMBL8671012 | 0.78 | FDPS (0.47) | — | |
| SCHEMBL3787961 | 0.78 | FDPS (0.47) | — | |
| SCHEMBL6672445 | 0.77 | — | — | |
| SCHEMBL841788 | 0.75 | — | — | |
| SCHEMBL1680330 | 0.74 | — | — | |
| SCHEMBL27260 | 0.74 | — | — | |
| SCHEMBL155115 | 0.74 | — | — | |
| SCHEMBL1647232 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586447-B | Benzodiazepine compound and preparation method and application thereof | 中国人民解放军第四军医大学 | 2021-01-29 | — | — | CN | claimed |
| CN-108586447-A | A kind of novel benzene diazepine compound and its preparation method and application | 中国人民解放军第四军医大学 | 2018-09-28 | — | — | CN | claimed |
| US-20240016775-A1 | ANTI-CORONAVIRUS APPLICATION OF POLY ADP RIBOSE POLYMERASE INHIBITOR | FUKANG (SHANGHAI) HEALTH TECHNOLOGY CO., LTD (CN) | 2024-01-18 | — | — | US | disclosed |
| US-11766443-B2 | Cyclopentathiophene carboxamide derivatives as platelet activating factor receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-09-26 | — | — | US | disclosed |
| CN-108586447-B | Benzodiazepine compound and preparation method and application thereof | 中国人民解放军第四军医大学 | 2021-01-29 | — | — | CN | disclosed |
| US-10449192-B2 | Phthalazinone derivatives | KUDO PHARMACEUTICALS LIMITED (GB) | 2019-10-22 | — | — | US | disclosed |
| US-10322107-B2 | N-methyl-N-(1-phenyl-2-(1-pyrrolidinyl)ethyl)-2-aminophenylacetamide derivatives agonists for the kappa opioid receptor | NEKTAR THERAPEUTICS (US) | 2019-06-18 | — | — | US | disclosed |
| CN-108586447-A | A kind of novel benzene diazepine compound and its preparation method and application | 中国人民解放军第四军医大学 | 2018-09-28 | — | — | CN | disclosed |
| US-20180185363-A1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARMACEUTICALS LIMITED (GB) | 2018-07-05 | — | — | US | disclosed |
| CN-104755476-B | Method for producing compound | 住友化学株式会社 | 2017-12-05 | — | — | CN | disclosed |
| US-20170226124-A1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARMACEUTICALS LIMITED (GB) | 2017-08-10 | — | — | US | disclosed |
| CN-101203227-B | Ergotrophic lactone compound | PFIZER | 2011-01-12 | — | — | CN | disclosed |
| US-7582611-B2 | Treating disorders of gastric motility; decreasing side effects of erythromycin A | PFIZER INC. (US) | 2009-09-01 | — | — | US | disclosed |
| EP-1888082-A4 | MOTILIDE COMPOUNDS | PFIZER (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2008086053-A1 | HCV INHIBITORS | VIROBAY, INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| CN-101203227-A | Ergotrophic lactone compound | PFIZER (US) | 2008-06-18 | — | — | CN | disclosed |
| WO-2008033932-A2 | BIARYLTHIAZOLE CARBOXYLIC ACID DERIVATIVES AS PROTEIN TYROSINE PHOSPHATASE-IB INHIBITORS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2008-03-20 | — | — | WO | disclosed |
| EP-1888082-A1 | MOTILIDE COMPOUNDS | Pfizer, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006127252-A1 | MOTILIDE COMPOUNDS | PFIZER, INC. (US) | 2006-11-30 | — | — | WO | disclosed |
| US-20060270616-A1 | Motilide compounds | PFIZER INC. | 2006-11-30 | — | — | US | disclosed |