Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.46 |
| ▸ | FDPS | P14324 | 9/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8956892 | 0.94 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL7557119 | 0.94 | TSHR (0.47) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL28605752 | 0.91 | GGPS1 (0.42) | TSHRTHRBGGPS1FDPSSMPD1 | |
| Phosphine SCHEMBL2473317 | 0.88 | TSHR (0.38) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL4875827 | 0.84 | TSHR (0.40) | TSHRTHRBGGPS1FDPS | |
| Ammonia Solution, Strong SCHEMBL6265351 | 0.81 | TSHR (0.38) | TSHRTHRBGGPS1FDPS | |
| SCHEMBL16970061 | 0.79 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL16969681 | 0.79 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL12348014 | 0.79 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL16970194 | 0.79 | TSHR (0.50) | TSHRTHRBGGPS1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123675-A1 | IMPROVED CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2009-10-08 | — | — | WO | disclosed |
| US-20090247783-A1 | CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2009-10-01 | — | — | US | disclosed |
| US-7582792-B2 | Carbonylation process | EASTMAN CHEMICAL COMPANY (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070293695-A1 | CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2007-12-20 | — | — | US | disclosed |
| EP-0584964-B1 | Process for the recovery of group VIII noble metals | BP CHEM INT LTD (GB) | 1998-08-26 | — | — | EP | disclosed |
| US-5364822-A | Process for the recovery of group VIII noble metals | BP CHEMICALS LIMITED (GB) | 1994-11-15 | — | — | US | disclosed |
| EP-0584964-A1 | Process for the recovery of group VIII noble metals | BP Chemicals Limited (GB) | 1994-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293695-A1 | CARBONYLATION PROCESS | CBR3, HAO2, CA4 | TSHR 1538/4885THRB 1030/4885GGPS1 2499/4885 |
| US-20090247783-A1 | CARBONYLATION PROCESS | CA4, HAO2, CA9 | TSHR 1657/4885THRB 1556/4885GGPS1 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.