⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854322 | 0.80 | LMNA (0.32) | — | |
| SCHEMBL538153 | 0.78 | — | — | |
| SCHEMBL2495980 | 0.78 | LMNA (0.36) | — | |
| SCHEMBL1358665 | 0.76 | — | — | |
| SCHEMBL248018 | 0.76 | — | — | |
| SCHEMBL5556024 | 0.76 | LMNA (0.41) | — | |
| SCHEMBL9854413 | 0.76 | LMNA (0.41) | — | |
| SCHEMBL5376186 | 0.76 | LMNA (0.41) | — | |
| SCHEMBL9854284 | 0.71 | — | — | |
| SCHEMBL1019091 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823047-B | Fluorine-containing imidazolium salt, and preparation method and application thereof | 西南石油大学 | 2025-05-30 | — | — | CN | disclosed |
| US-20250129077-A1 | SUBSTITUTED PURINES AS TLR7 AGONISTS | Primmune Therapeutics, Inc. | 2025-04-24 | — | — | US | disclosed |
| CN-119823047-A | Fluorine-containing imidazolium salt, and preparation method and application thereof | 西南石油大学 | 2025-04-15 | — | — | CN | disclosed |
| EP-4512816-A2 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| CN-112533607-B | TLR7 agonists | 普利缪尼治疗学股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3801538-B1 | TLR7 AGONISTS | PRIMMUNE THERAPEUTICS INC (US) | 2024-10-02 | — | — | EP | disclosed |
| US-12037335-B2 | Substituted purines as TLR7 agonists | Primmune Therapeutics, Inc. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20220098198-A1 | SUBSTITUTED PURINES AS TLR7 AGONISTS | Primmune Therapeutics, Inc. | 2022-03-31 | — | — | US | disclosed |
| US-11059824-B2 | Substituted purines as TLR7 agonists | Primmune Therapeutics, Inc. (US) | 2021-07-13 | — | — | US | disclosed |
| EP-3801538-A1 | TLR7 AGONISTS | Primmune Therapeutics, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| WO-2007053671-A1 | AEROSOL PROPELLANTS COMPRISING UNSATURATED FLUOROCARBONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070102021-A1 | Solvent compositions comprising unsaturated fluorinated hydrocarbons | THE CHEMOURS COMPANY FC, LLC | 2007-05-10 | — | — | US | disclosed |
| US-20070098646-A1 | Aerosol propellants comprising unsaturated fluorocarbons | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-05-03 | — | — | US | disclosed |
| US-20070100011-A1 | Blowing agents for forming foam comprising unsaturated fluorocarbons | THE CHEMOURS COMPANY FC, LLC | 2007-05-03 | — | — | US | disclosed |
| US-20070100009-A1 | Methods for making foams using blowing agents comprising unsaturated fluorocarbons | THE CHEMOURS COMPANY FC, LLC | 2007-05-03 | — | — | US | disclosed |
| US-20070100010-A1 | Blowing agents for forming foam comprising unsaturated fluorocarbons | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-05-03 | — | — | US | disclosed |
| EP-1731518-A1 | CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2006-12-13 | — | — | EP | disclosed |
| EP-0252736-B1 | PROCESS FOR PREPARING FLUORINE-CONTAINING CARBOXYLIC ACID ESTER | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-24 | — | — | EP | disclosed |
| US-4855487-A | Process for preparing fluorine-containing carboxylic acid ester | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0252736-A2 | Process for preparing fluorine-containing carboxylic acid ester | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1988-01-13 | — | — | EP | disclosed |