SCHEMBL3860743

SCHEMBL3860743

O=C1C=CC(c2cc(=O)c3c(O)c(O)c(O)cc3o2)=CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRS Q13332 7/20 0.55
CREB1 P16220 5/20 0.55
KMT2A Q03164 4/20 0.55
ABCB1 P08183 4/20 0.55
FTO Q9C0B1 3/20 0.55
GABRP O00591 3/20 0.55
GABRD O14764 3/20 0.55
GABRA1 P14867 3/20 0.55
GABRB1 P18505 3/20 0.55
GABRG2 P18507 3/20 0.55
GABRB3 P28472 3/20 0.55
GABRA5 P31644 3/20 0.55
GABRA3 P34903 3/20 0.55
GABRA2 P47869 3/20 0.55
GABRB2 P47870 3/20 0.55
GABRA4 P48169 3/20 0.55
GABRE P78334 3/20 0.55
GABRA6 Q16445 3/20 0.55
GABRG1 Q8N1C3 3/20 0.55
GABRG3 Q99928 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11662442 0.74 PTPRS (0.74) PTPRSCREB1KMT2AABCB1FTO
Scutellarein SCHEMBL142093 0.71 KMT2A (1.00) PTPRSCREB1KMT2AABCB1FTO
Scutellarein SCHEMBL29692708 0.71 KMT2A (1.00) PTPRSCREB1KMT2AABCB1FTO
Baicalein SCHEMBL29385549 0.71 ABCB1 (1.00) PTPRSCREB1KMT2AABCB1FTO
Baicalein SCHEMBL5695785 0.71 ABCB1 (1.00) PTPRSCREB1KMT2AABCB1FTO
Baicalein SCHEMBL139617 0.71 ABCB1 (1.00) PTPRSCREB1KMT2AABCB1FTO
Scutellarein SCHEMBL29004586 0.71 KMT2A (1.00) PTPRSCREB1KMT2AABCB1FTO
SCHEMBL5163483 0.70 KMT2A (0.71) PTPRSCREB1KMT2AABCB1FTO
Scutellarein SCHEMBL1900314 0.70 KMT2A (0.97) PTPRSCREB1KMT2AABCB1FTO
Scutellarein SCHEMBL15090395 0.70 KMT2A (0.97) PTPRSCREB1KMT2AABCB1FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1556031-A4 CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF JENKEN BIOSCIENCES INC (US) 2009-03-25 EP disclosed
EP-1556031-A2 CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF Jenken Bioscience, Inc. (US) 2005-07-27 EP disclosed
WO-2004037193-A2 CHROMONES AND CHROMONE DERIVATIVES AND USES THEREOF JENKEN BIOSCIENCES, INC. (US) 2004-05-06 WO disclosed