SCHEMBL5163483

SCHEMBL5163483

O=c1cc(-c2ccccc2O)oc2cc(O)c(O)c(O)c12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.71
PTPRS Q13332 6/20 0.71
MEN1 O00255 6/20 0.71
TP53 P04637 5/20 0.71
CYP3A4 P08684 4/20 0.71
CYP2D6 P10635 4/20 0.71
MAPT P10636 4/20 0.71
CYP2C9 P11712 4/20 0.71
CYP2C19 P33261 4/20 0.71
GABRP O00591 3/20 0.71
GABRD O14764 3/20 0.71
GABRA1 P14867 3/20 0.71
GABRB1 P18505 3/20 0.71
GABRG2 P18507 3/20 0.71
GABRB3 P28472 3/20 0.71
GABRA5 P31644 3/20 0.71
GABRA3 P34903 3/20 0.71
GABRA2 P47869 3/20 0.71
GABRB2 P47870 3/20 0.71
GABRA4 P48169 3/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17258302 0.87 PTPRS (0.66) KMT2APTPRSMEN1TP53CYP3A4
SCHEMBL2961755 0.84 PTPRS (0.61) KMT2APTPRSMEN1TP53CYP3A4
SCHEMBL6906640 0.84 CREB1 (0.75) KMT2APTPRSMEN1TP53CYP3A4
Baicalein SCHEMBL5695785 0.83 ABCB1 (1.00) KMT2APTPRSMEN1TP53CYP3A4
Baicalein SCHEMBL29385549 0.83 ABCB1 (1.00) KMT2APTPRSMEN1TP53CYP3A4
Baicalein SCHEMBL139617 0.83 ABCB1 (1.00) KMT2APTPRSMEN1TP53CYP3A4
SCHEMBL4649638 0.83 MEN1 (0.78) KMT2AMEN1TP53CYP3A4CYP2D6
Baicalein SCHEMBL28826034 0.82 ABCB1 (0.97) KMT2APTPRSMEN1TP53CYP3A4
Baicalein SCHEMBL28372093 0.82 ABCB1 (0.97) KMT2APTPRSMEN1TP53CYP3A4
SCHEMBL3708991 0.82 MEN1 (1.00) KMT2APTPRSMEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859557-B1 FOODS AND BEVERAGES CONTAINING ANTHOCYANINS STABILIZED BY PLANT EXTRACTS NATUREX INC (US) 2007-03-21 EP claimed
CN-113694142-A Preparation method of anti-aging traditional Chinese medicine formula by utilizing probiotic fermentation 徐晓英 2021-11-26 CN disclosed
US-7045158-B2 Standardized extracts of Scutellaria lateriflora WOLFSON PHILIP E 2006-05-16 US disclosed
US-20050025845-A1 Standardized extracts of scutellaria lateriflora WOLFSON PHILIP E (US) 2005-02-03 US disclosed
US-6740343-B2 ANXIOLYTIC AGENT, SLEEP DISORDERS, ANTICONVULSANTS, MUSCLE RELAXANTS PHYTOS, INC. 2004-05-25 US disclosed
US-20030054050-A1 Standardized extracts of scutellaria lateriflora PHYTOS, INC. 2003-03-20 US disclosed