Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3860822 | 1.00 | KMT2A (0.43) | KMT2AHSD17B1HSD17B2MGLLBRD4 | |
| SCHEMBL3855476 | 1.00 | KMT2A (0.43) | KMT2AHSD17B1HSD17B2MGLLBRD4 | |
| SCHEMBL3863242 | 0.91 | KMT2A (0.46) | KMT2AHSD17B1HSD17B2MGLLBRD4 | |
| SCHEMBL3860943 | 0.91 | KMT2A (0.46) | KMT2AHSD17B1HSD17B2MGLLBRD4 | |
| SCHEMBL3860354 | 0.88 | KMT2A (0.46) | KMT2AMEN1GPR3 | |
| SCHEMBL3855998 | 0.88 | KMT2A (0.46) | KMT2AMEN1GPR3 | |
| SCHEMBL3855449 | 0.88 | KMT2A (0.46) | KMT2AMEN1GPR3 | |
| SCHEMBL3854470 | 0.86 | MGLL (0.41) | KMT2AHSD17B1HSD17B2MGLLBRD4 | |
| SCHEMBL3854609 | 0.86 | MGLL (0.41) | KMT2AHSD17B1HSD17B2MGLLBRD4 | |
| SCHEMBL3853980 | 0.86 | MGLL (0.41) | KMT2AHSD17B1HSD17B2MGLLBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585871-B2 | 4-{[(6R)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; 3-{[(6S)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; 4-{[(6S)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; cytokine expression | WYETH (US) | 2009-09-08 | — | — | US | claimed |
| CN-101052623-A | Phenanthridine carbonyl phenols as cytokine modulators | WYETH CORP (US) | 2007-10-10 | — | — | CN | claimed |
| US-20060058337-A1 | Phenanthridine carbonyl phenols | WYETH (US) | 2006-03-16 | — | — | US | claimed |
| US-7585871-B2 | 4-{[(6R)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; 3-{[(6S)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; 4-{[(6S)-8-fluoro-6-methylphenanthridin-5(6H)-yl]carbonyl}phenol; cytokine expression | WYETH (US) | 2009-09-08 | — | — | US | disclosed |
| CN-101052623-A | Phenanthridine carbonyl phenols as cytokine modulators | WYETH CORP (US) | 2007-10-10 | — | — | CN | disclosed |
| EP-1784391-A1 | PHENANTHRIDINE CARBONYL PHENOLS AS CYTOKINE EXPRESSION MODULATORS | Wyeth (US) | 2007-05-16 | — | — | EP | disclosed |
| US-20060058337-A1 | Phenanthridine carbonyl phenols | WYETH (US) | 2006-03-16 | — | — | US | disclosed |
| WO-2006028875-A1 | PHENANTHRIDINE CARBONYL PHENOLS AS CYTOKINE MODULATORS | WYETH (US) | 2006-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058337-A1 | Phenanthridine carbonyl phenols | MT-CO2, PAH, CBR3 | KMT2A 1282/4885HSD17B1 2706/4885HSD17B2 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.