Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.63 |
| ▸ | MMP13 | P45452 | 2/20 | 0.63 |
| ▸ | MMP2 | P08253 | 2/20 | 0.63 |
| ▸ | MMP8 | P22894 | 1/20 | 0.63 |
| ▸ | APP | P05067 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | BACE1 | P56817 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.63 |
| ▸ | STAT3 | P40763 | 2/20 | 0.63 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 2/20 | 0.63 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862013 | 1.00 | MMP9 (0.63) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL5598941 | 0.89 | APP (0.73) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL5598945 | 0.89 | APP (0.73) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL12088589 | 0.84 | MMP9 (0.72) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL3855730 | 0.81 | KMT2A (0.52) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL3855728 | 0.81 | KMT2A (0.52) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL10001150 | 0.81 | KMT2A (0.78) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL3858965 | 0.80 | APP (0.64) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL3858963 | 0.80 | APP (0.64) | MMP9MMP13MMP2MMP8APP | |
| SCHEMBL30504665 | 0.80 | MMP9 (0.71) | MMP9MMP13MMP2MMP8APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589123-B2 | Chemical compounds | PHYTOPHARM PLC (GB) | 2009-09-15 | — | — | US | claimed |
| US-7589123-B2 | Chemical compounds | PHYTOPHARM PLC (GB) | 2009-09-15 | — | — | US | disclosed |
| CN-101511350-A | Dioxo-alkanes and dioxo-alkenes | PHYTOPHARM PLC (GB) | 2009-08-19 | — | — | CN | disclosed |
| US-20080045591-A1 | Chemical Compounds | VECTURA LIMITED (GB) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045591-A1 | Chemical Compounds | CYP11B1, CYP11B2, CYP2S1 | MMP9 2828/4885MMP13 4086/4885MMP2 4449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.