⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543501 | 0.72 | — | — | |
| SCHEMBL3945142 | 0.67 | — | — | |
| SCHEMBL317785 | 0.67 | KDM4E (0.36) | — | |
| SCHEMBL235759 | 0.67 | KDM4E (0.36) | — | |
| SCHEMBL1329678 | 0.65 | — | — | |
| SCHEMBL293591 | 0.64 | — | — | |
| Ammonia Solution, Strong SCHEMBL9748105 | 0.64 | KDM4E (0.34) | — | |
| Hydrochloric Acid SCHEMBL10694332 | 0.64 | KDM4E (0.34) | — | |
| Hydrochloric Acid SCHEMBL10694337 | 0.64 | KDM4E (0.34) | — | |
| SCHEMBL2644847 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373825-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2024-05-29 | — | — | EP | claimed |
| US-20230303584-A1 | 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF | CIT THERAPEUTICS LLC | 2023-09-28 | — | — | US | claimed |
| WO-2023137297-A2 | 5,6-DIHYDRO-4H-THIENO[2,3-C]PYRROLE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2023-07-20 | — | — | WO | claimed |
| WO-2023004376-A1 | NITRILE SUMO INHIBITORS AND USES THEREOF | Suvalent Therapeutics, Inc. (US) | 2023-01-26 | — | — | WO | claimed |
| CN-114728009-A | Preventing or treating diseases and disorders associated with tissue damage | 李晓祥 | 2022-07-08 | — | — | CN | claimed |
| WO-2021150918-A1 | 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF | ONCOVALENT THERAPEUTICS INC. (US) | 2021-07-29 | — | — | WO | claimed |
| WO-2021024141-A1 | PREVENTION OR TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE | LI XIAOXIANG (CN) | 2021-02-11 | — | — | WO | claimed |
| CN-102993250-B | -9-deoxidation-9A-azepine-9A-the a-homoerythromycin A derivatives that C-3 replaces | Luoyang Huizhong Animal Medicine Co., Ltd. (CN) | 2016-02-10 | — | — | CN | claimed |
| EP-1844022-B1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI SCIENCE CO LTD (KR) | 2013-08-14 | — | — | EP | claimed |
| CN-102993250-A | C-3 substituted-9-deoxidized-9A-aza-9A-high erythromycin A derivative | LUOYANG HUIZHONG ANIMAL MEDICINE CO LTD | 2013-03-27 | — | — | CN | claimed |
| US-20020156026-A1 | C-4\"-substituted macrolide derivatives | BRONK BRAIN SCOTT (US) | 2002-10-24 | — | — | US | claimed |
| US-6407074-B1 | BACTERICIDES, ANTIBIOTICS | PFIZER INC | 2002-06-18 | — | — | US | claimed |
| US-20020061858-A1 | 4\"-substituted-9-deoxo-9A-AZA-9A-homoerythromycin a derivatives | PFIZER INC. | 2002-05-23 | — | — | US | claimed |
| EP-1024145-A2 | Novel azalides and methods of making same | Pfizer Products Inc. (US) | 2000-08-02 | — | — | EP | claimed |
| CN-1259955-A | C-4'-substituted macrolide derivatives | PFIZER PROD INC (US) | 2000-07-12 | — | — | CN | claimed |
| CN-1259136-A | 4' -substituted-9-deoxo-9A-aza-9A-homoerythromycin A derivatives | PFIZER PROD INC (US) | 2000-07-05 | — | — | CN | claimed |
| EP-0988309-A1 | C-4''-SUBSTITUTED MACROLIDE DERIVATIVES | Pfizer Products Inc. (US) | 2000-03-29 | — | — | EP | claimed |
| EP-0988310-A1 | 4\"-SUBSTITUTED-9-DEOXO-9A-AZA-9A-HOMOERYTHROMYCIN A DERIVATIVES | Pfizer Products Inc. (US) | 2000-03-29 | — | — | EP | claimed |
| WO-1998056801-A1 | C-4''-SUBSTITUTED MACROLIDE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1998-12-17 | — | — | WO | claimed |
| WO-1998056802-A1 | 4'-SUBSTITUTED-9-DEOXO-9A-AZA-9A-HOMOERYTHROMYCIN A DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1998-12-17 | — | — | WO | claimed |