SCHEMBL3862500

SCHEMBL3862500

O=[N+]([O-])/C=C/c1cccc(C(F)(F)F)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 12/20 1.00
MAOA P21397 2/20 0.66
MAOB P27338 2/20 0.66
VCP P55072 1/20 0.58
NFE2L2 Q16236 1/20 0.53
TLR4 O00206 1/20 0.53
TLR2 O60603 1/20 0.53
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3862508 1.00 FBP1 (1.00) FBP1MAOAMAOBVCPNFE2L2
SCHEMBL30592090 1.00 FBP1 (1.00) FBP1MAOAMAOBVCPNFE2L2
SCHEMBL28653968 0.83 FBP1 (0.71) FBP1MAOAMAOBVCPTLR4
SCHEMBL22291197 0.83 FBP1 (0.71) FBP1MAOAMAOBVCPTLR4
SCHEMBL8471408 0.83 FBP1 (0.68) FBP1MAOAMAOBVCPMEN1
SCHEMBL8471407 0.83 FBP1 (0.68) FBP1MAOAMAOBVCPMEN1
SCHEMBL7412199 0.82 FBP1 (0.70) FBP1MAOAMAOBVCP
SCHEMBL15054765 0.80 FBP1 (0.66) FBP1MAOAMAOBVCPTLR4
SCHEMBL15054763 0.80 FBP1 (0.66) FBP1MAOAMAOBVCPTLR4
SCHEMBL794128 0.79 FBP1 (1.00) FBP1MAOAMAOBVCPTLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7132219-B2 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE INC. (US) 2006-11-07 US claimed
EP-1397260-A4 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE INC (US) 2006-03-08 EP claimed
EP-1397260-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION Brewer Science, Inc. (US) 2004-03-17 EP claimed
US-20030219541-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-11-27 US claimed
US-20030064608-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition SABNIS RAM W (US) 2003-04-03 US claimed
US-20030054117-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-03-20 US claimed
WO-2002062593-A1 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2002-08-15 WO claimed
US-5744273-A Laminatable backing substrates containing fluoro compounds for improved toner flow XEROX CORPORATION (US) 1998-04-28 US claimed
EP-4086240-B1 PYRROLIDINONE HERBICIDES FMC CORP (US) 2025-02-05 EP disclosed
US-12077503-B2 Substituted cyclic amides and their use as herbicides FMC CORPORATION (US) 2024-09-03 US disclosed
US-20240025853-A1 SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES FMC CORPORATION 2024-01-25 US disclosed
US-11787765-B2 Substituted cyclic amides and their use as herbicides FMC CORPORATION (US) 2023-10-17 US disclosed
CN-110407730-B Pyrrolidone herbicides FMC 公司 2023-09-08 CN disclosed
US-20230270111-A1 PYRROLIDINONES HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY 2023-08-31 US disclosed
WO-2003087233-A2 POLYMERIC ANTIREFLECTIVE COATINGS DEPOSITED BY PLASMA ENHANCED CHEMICAL VAPOR DEPOSITION BREWER SCIENCE, INC. (US) 2003-10-23 WO disclosed
US-20030064608-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition SABNIS RAM W (US) 2003-04-03 US disclosed
US-20030054117-A1 Polymeric antireflective coatings deposited by plasma enhanced chemical vapor deposition BREWER SCIENCE, INC. 2003-03-20 US disclosed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 US disclosed
US-5763470-A Benzopyran compounds and methods for their use SUGEN INC. (US) 1998-06-09 US disclosed
WO-1988003147-A1 SELECTED N6-SUBSTITUTED ADENOSINES HAVING SELECTIVE A2 BINDING ACTIVITY WARNER-LAMBERT COMPANY (US) 1988-05-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11787765-B2 Substituted cyclic amides and their use as herbicides NIT2, ARG1, CNPY2 FBP1 3219/4885MAOA 1121/4885MAOB 841/4885
US-20240025853-A1 SUBSTITUTED CYCLIC AMIDES AND THEIR USE AS HERBICIDES NIT2, ARG1, CNPY2 FBP1 3184/4885MAOA 1104/4885MAOB 837/4885
US-20230270111-A1 PYRROLIDINONES HERBICIDES DDT, ARG1, CYP1B1 FBP1 1229/4885MAOA 1167/4885MAOB 864/4885
US-12077503-B2 Substituted cyclic amides and their use as herbicides NIT2, ARG1, CNPY2 FBP1 3184/4885MAOA 1104/4885MAOB 837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.