⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55353 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL14689074 | 0.79 | ALDH1A1 (0.37) | — | |
| SCHEMBL16656334 | 0.79 | — | — | |
| SCHEMBL19418536 | 0.75 | — | — | |
| SCHEMBL55354 | 0.75 | — | — | |
| SCHEMBL23384087 | 0.75 | — | — | |
| SCHEMBL4826277 | 0.75 | — | — | |
| SCHEMBL9436380 | 0.75 | — | — | |
| SCHEMBL8608523 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL17225016 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582476-B2 | Artificial cell comprising mutant estrogen receptor | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-09-01 | — | — | US | disclosed |
| EP-1237925-B1 | MUTANT ER-ALPHA AND TEST SYSTEMS FOR TRANSACTIVATION | SUMITOMO CHEMICAL CO (JP) | 2007-07-11 | — | — | EP | disclosed |
| US-20030207380-A1 | Mutant era and test systems for transactivation | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-11-06 | — | — | US | disclosed |
| EP-1237925-A1 | MUTANT ER$g(a) AND TEST SYSTEMS FOR TRANSACTIVATION | Sumitomo Chemical Company, Limited (JP) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042307-A1 | MUTANT ERα AND TEST SYSTEMS FOR TRANSACTIVATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-06-14 | — | — | WO | disclosed |
| EP-0407942-B1 | Streptokinase proteins, corresponding genes, corresponding plasmid recombinants, corresponding transformants and processes for preparing same | OTSUKA PHARMA CO LTD (JP) | 1995-10-11 | — | — | EP | disclosed |
| US-5240845-A | Having specified amino acid sequence | OTSUKA PHARMACEUTICAL FACTORY, LTD. (JP) | 1993-08-31 | — | — | US | disclosed |
| EP-0407942-A2 | Streptokinase proteins, corresponding genes, corresponding plasmid recombinants, corresponding transformants and processes for preparing same | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1991-01-16 | — | — | EP | disclosed |