Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 3/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863802 | 1.00 | GAA (0.46) | GAAERN1IP6K1IP6K3IP6K2 | |
| SCHEMBL2533346 | 0.92 | ERN1 (0.44) | ERN1SLC6A2SLC6A4KMT2AAURKA | |
| SCHEMBL2536942 | 0.91 | IP6K1 (0.49) | GAAIP6K1IP6K3IP6K2SLC6A2 | |
| SCHEMBL2536938 | 0.91 | IP6K1 (0.49) | GAAIP6K1IP6K3IP6K2SLC6A2 | |
| SCHEMBL2538639 | 0.90 | AURKA (0.48) | GAAIP6K1IP6K3IP6K2SLC6A2 | |
| SCHEMBL2532598 | 0.90 | AURKA (0.48) | GAAIP6K1IP6K3IP6K2SLC6A2 | |
| SCHEMBL12225947 | 0.87 | ERN1 (0.56) | ERN1SLC6A2SLC6A4KMT2AAURKA | |
| SCHEMBL2532650 | 0.86 | IP6K1 (0.44) | GAAIP6K1IP6K3IP6K2SLC6A2 | |
| SCHEMBL2532652 | 0.86 | IP6K1 (0.44) | GAAIP6K1IP6K3IP6K2SLC6A2 | |
| SCHEMBL2533347 | 0.84 | ERN1 (0.43) | ERN1SLC6A2SLC6A4AURKATPX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2080751-A1 | CARBOXYLIC ACID DERIVATIVE | Institute of Medicinal Molecular Design, Inc. (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-20080275116-A1 | Carboxilic acid derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275116-A1 | Carboxilic acid derivatives | SERPINE1, CTRL, SERPINC1 | GAA 2245/4885ERN1 918/4885IP6K1 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.