Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.57 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459653 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAMMP9MMP8 | |
| SCHEMBL1200801 | 0.81 | ALDH1A1 (0.75) | ALDH1A1TBXA2RMAPTATMGAA | |
| SCHEMBL28339828 | 0.81 | BCAT1 (0.55) | ALDH1A1TBXA2RBCAT1KAT6AMAPT | |
| SCHEMBL7980857 | 0.79 | BCAT1 (0.45) | ALDH1A1TBXA2RBCAT1KAT6AMAPT | |
| Hydrazine SCHEMBL11854301 | 0.79 | ALDH1A1 (0.71) | ALDH1A1TBXA2RMAPTATMGAA | |
| SCHEMBL28150870 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1BCAT1KAT6AGAAMMP9 | |
| Hydrochloric Acid SCHEMBL7447734 | 0.78 | BCAT1 (0.44) | ALDH1A1TBXA2RBCAT1KAT6AMAPT | |
| SCHEMBL15482049 | 0.77 | CYP2C19 (0.59) | ALDH1A1TBXA2RBCAT1KAT6AGAA | |
| SCHEMBL911198 | 0.75 | ALDH1A1 (0.87) | ALDH1A1TBXA2RMAPTATMGAA | |
| SCHEMBL11829145 | 0.75 | BCAT1 (0.61) | ALDH1A1BCAT1KAT6AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047425-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1044001-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-1007026-A4 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1100506-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2002-06-26 | — | — | EP | disclosed |
| EP-1105389-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-1105389-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1100506-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2001-05-23 | — | — | EP | disclosed |
| EP-0946165-A4 | INTEGRIN ANTAGONISTS | MERCK & CO INC (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1047425-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-1044001-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000009503-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-2000006169-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0946165-A1 | INTEGRIN ANTAGONISTS | Merck & Co., Inc. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1999030709-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999030713-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999031061-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999031099-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1998046220-A1 | COMBINATION THERAPY FOR THE PREVENTION AND TREATMENT OF OSTEOPOROSIS | MERCK & CO., INC. (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998031359-A1 | INTEGRIN ANTAGONISTS | MERCK & CO., INC. (US) | 1998-07-23 | — | — | WO | disclosed |
| WO-1998018460-A1 | INTEGRIN ANTAGONISTS | MERCK & CO., INC. (US) | 1998-05-07 | — | — | WO | disclosed |