Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.62 |
| ▸ | TOP2A | P11388 | 1/20 | 0.62 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18063662 | 0.87 | TOP1 (0.59) | TOP1TOP2ATOP2BNPC1RAB9A | |
| SCHEMBL6799613 | 0.86 | MEN1 (0.58) | TOP1TOP2ATOP2BNPC1RAB9A | |
| SCHEMBL6029925 | 0.84 | NPC1 (0.82) | TOP1TOP2ATOP2BNPC1RAB9A | |
| SCHEMBL462324 | 0.83 | MEN1 (0.66) | TOP1TOP2ATOP2BNPC1RAB9A | |
| SCHEMBL3661213 | 0.83 | NPC1 (0.74) | TOP1TOP2ATOP2BNPC1RAB9A | |
| SCHEMBL4946074 | 0.82 | NPC1 (0.73) | TOP1TOP2ATOP2BNPC1RAB9A | |
| SCHEMBL1470784 | 0.82 | NPC1 (0.73) | TOP1TOP2ATOP2BNPC1RAB9A | |
| SCHEMBL28104457 | 0.82 | MEN1 (0.73) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL3860173 | 0.82 | TOP1 (0.59) | TOP1TOP2ATOP2BNPC1RAB9A | |
| SCHEMBL11587889 | 0.81 | TOP1 (0.62) | TOP1TOP2ATOP2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915337-A4 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORP (KR) | 2009-04-22 | — | — | EP | disclosed |
| US-20080280989-A1 | Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same | AMOREPACIFIC CORPORATION (KR) | 2008-11-13 | — | — | US | disclosed |
| CN-101243042-A | Hydroxybenzamide derivatives, the method for preparing thereof and the cosmetic composition containing the same | AMOREPACIFIC CORP (KR) | 2008-08-13 | — | — | CN | disclosed |
| EP-1915337-A1 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | Amorepacific Corporation (KR) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007021067-A1 | HYDROXYBENZAMIDE DERIVATIVES, THE METHOD FOR PREPARING THEREOF AND THE COSMETIC COMPOSITION CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280989-A1 | Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same | H1-0, HAAO, H1-10 | TOP1 1513/4885TOP2A 1921/4885TOP2B 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.