Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529107 | 0.89 | SMN1; SMN2 (0.53) | HIF1ASMN1; SMN2CYP2C19LMNACYP1A2 | |
| SCHEMBL7289855 | 0.89 | HIF1A (0.53) | HIF1ASMN1; SMN2CYP2C19LMNACYP1A2 | |
| SCHEMBL10710068 | 0.89 | SMN1; SMN2 (0.53) | HIF1ASMN1; SMN2CYP2C19LMNACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL25250245 | 0.87 | SMN1; SMN2 (0.52) | HIF1ASMN1; SMN2CYP2C19LMNACYP1A2 | |
| Phosphoric Acid SCHEMBL8654813 | 0.82 | FDPS (0.50) | HIF1ASMN1; SMN2ALDH1A1RIPK1ARG1 | |
| SCHEMBL7355721 | 0.81 | HIF1A (0.43) | HIF1ASMN1; SMN2CYP2C19LMNACYP1A2 | |
| SCHEMBL15211825 | 0.81 | CETP (0.44) | ALDH1A1 | |
| SCHEMBL15211964 | 0.81 | CETP (0.44) | ALDH1A1 | |
| SCHEMBL27681244 | 0.80 | SMN1; SMN2 (0.47) | HIF1ASMN1; SMN2CYP2C19LMNACYP1A2 | |
| SCHEMBL27674017 | 0.79 | SMN1; SMN2 (0.47) | HIF1ASMN1; SMN2CYP2C19LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595055-B2 | Pharmaceutical composition comprising an extract or compounds isolated from Elfvingia applanata for the prevention and the treatment of diabetes and diabetic complications | Son, Dal-Hoon (CA) | 2009-09-29 | — | — | US | disclosed |
| US-20070224213-A1 | Pharmaceutical Composition Comprising an Extract or Compounds Isolated from Elfvingia Applanata for the Prevention and the Treatment of Diabetes and Diabetic Complications | SON, DAL-HOON (CA) | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070224213-A1 | Pharmaceutical Composition Comprising an Extract or Compounds Isolated from Elfvingia Applanata for the Prevention and the Treatment of Diabetes and Diabetic Complications | DPP7, DPP4, ELF3 | HIF1A 678/4885SMN1; SMN2 3500/4885CYP2C19 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.