Methacrylic Acid

Methacrylic Acid

SCHEMBL3864596

C(OCC1CO1)C1CO1.C=C(C)C(=O)O.C=C(C)C(=O)Oc1ccc(C(C)(C)c2ccc(O)cc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
ALDH1A1 P00352 6/20 0.47
MEN1 O00255 4/20 0.47
HPGD P15428 3/20 0.47
TSHR P16473 3/20 0.47
TP53 P04637 2/20 0.47
MAPT P10636 2/20 0.47
CYP1A2 P05177 1/20 0.47
PPARG P37231 1/20 0.47
HIF1A Q16665 1/20 0.47
ELANE P08246 2/20 0.38
MIF P14174 1/20 0.37
ATM Q13315 1/20 0.36
ESR1 P03372 2/20 0.34
CYP3A4 P08684 2/20 0.34
ESR2 Q92731 2/20 0.34
AR P10275 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7923720 0.97 KMT2A (0.50) KMT2AALDH1A1MEN1HPGDTSHR
Bisphenol A SCHEMBL28736539 0.91 TSHR (0.49) KMT2AALDH1A1MEN1HPGDTSHR
SCHEMBL11861222 0.86 ALDH1A1 (0.46) KMT2AALDH1A1MEN1HPGDTSHR
Methacrylic Acid SCHEMBL17868328 0.86 KMT2A (0.40) KMT2AALDH1A1MEN1HPGDTSHR
SCHEMBL3389975 0.86 KMT2A (0.44) KMT2AALDH1A1MEN1HPGDTSHR
Bisphenol A SCHEMBL28353133 0.85 ALDH1A1 (0.59) KMT2AALDH1A1MEN1HPGDTSHR
Bicarbonate SCHEMBL10771552 0.84 TSHR (0.53) KMT2AALDH1A1MEN1HPGDTSHR
SCHEMBL712702 0.84 ALDH1A1 (0.68) KMT2AALDH1A1MEN1HPGDTSHR
Bisphenol A SCHEMBL30171376 0.83 ALDH1A1 (0.56) KMT2AALDH1A1MEN1HPGDTSHR
SCHEMBL9011361 0.82 ALDH1A1 (0.51) KMT2AALDH1A1MEN1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160185887-A1 POLYMERIZABLE COMPOSITION FOR HIGH-REFRACTIVE OPTICAL MATERIAL AND METHOD FOR PREPARING HIGH-REFRACTIVE OPTICAL MATERIAL KOC SOLUTION CO., LTD. (KR) 2016-06-30 US claimed
CN-113993905-B Method for setting use condition of polymerization catalyst, method for setting polymerization condition, and method for producing optical material 三井化学株式会社 2023-03-31 CN disclosed
CN-111868099-B Method for setting polymerization conditions and method for producing optical material 三井化学株式会社 2022-12-16 CN disclosed
CN-109689698-B Polymerizable composition for optical material and molded article 三井化学株式会社 2022-05-31 CN disclosed
CN-113993905-A Method for setting use condition of polymerization catalyst, method for setting polymerization condition, and method for producing optical material 三井化学株式会社 2022-01-28 CN disclosed
CN-109716216-B Photochromic lens and polymerizable composition 三井化学株式会社 2021-05-07 CN disclosed
CN-107949584-B Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens 三井化学株式会社 2021-04-27 CN disclosed
US-10921489-B2 Polymerizable composition for optical material, optical material obtained from the composition, and plastic lens MITSUI CHEMICALS, INC. (JP) 2021-02-16 US disclosed
WO-2020256057-A1 USE CONDITION SETTING METHOD FOR POLYMERIZATION CATALYST, POLYMERIZATION CONDITION SETTING METHOD, AND METHOD FOR PRODUCING OPTICAL MATERIAL 三井化学株式会社 2020-12-24 WO disclosed
CN-111868099-A Method for setting polymerization conditions and method for producing optical material 三井化学株式会社 2020-10-30 CN disclosed
EP-3351564-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND OPTICAL MATERIAL AND PLASTIC LENS OBTAINED FROM COMPOSITION MITSUI CHEMICALS INC (JP) 2020-04-15 EP disclosed
WO-2019187176-A1 METHOD FOR SETTING POLYMERIZATION CONDITIONS AND METHOD FOR PRODUCING OPTICAL MATERIAL 三井化学株式会社 2019-10-03 WO disclosed
EP-3521907-A1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION Mitsui Chemicals, Inc. (JP) 2019-08-07 EP disclosed
US-20190211258-A1 PHOTOCHROMIC LENS AND POLYMERIZABLE COMPOSITION MITSUI CHEMICALS, INC. (JP) 2019-07-11 US disclosed
US-20180341043-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL OBTAINED FROM THE COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS, INC. (JP) 2018-11-29 US disclosed
EP-3351564-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, AND OPTICAL MATERIAL AND PLASTIC LENS OBTAINED FROM COMPOSITION Mitsui Chemicals, Inc. (JP) 2018-07-25 EP disclosed
US-20160185887-A1 POLYMERIZABLE COMPOSITION FOR HIGH-REFRACTIVE OPTICAL MATERIAL AND METHOD FOR PREPARING HIGH-REFRACTIVE OPTICAL MATERIAL KOC SOLUTION CO., LTD. (KR) 2016-06-30 US disclosed
US-7553881-B2 Dental materials based on radically polymerizable macromers with antimicrobial effect IVOCLAR VIVADENT AG (LI) 2009-06-30 US disclosed
US-20070254979-A1 Dental materials based on radically polymerizable macromers with antimicrobial effect IVOCLAR VIVADENT AG (LI) 2007-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070254979-A1 Dental materials based on radically polymerizable macromers with antimicrobial effect MSR1, PAM, C1R KMT2A 3440/4885ALDH1A1 2170/4885MEN1 2242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.