SCHEMBL38650792

SCHEMBL38650792

COC(=O)CC1c2ccccc2N(C)S(=O)(=O)c2ccc(OC)cc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
HTT P42858 1/20 0.46
GAA P10253 3/20 0.39
POLB P06746 2/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
NPC1 O15118 1/20 0.38
NR1I2 O75469 3/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
OPRD1 P41143 1/20 0.38
EGFR P00533 1/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38651056 0.88 ALDH1A1 (0.39) GAAPOLBNR1I2OPRM1DRD3
SCHEMBL38650796 0.87 EGFR (0.43) CYP1A2CYP2C9CYP2C19HTTNR1I2
SCHEMBL38651026 0.87 NR1I2 (0.38) NR1I2OPRM1DRD3OPRD1EGFR
SCHEMBL38651042 0.87 NR1I2 (0.48) NR1I2OPRM1DRD3OPRD1EGFR
SCHEMBL38650960 0.87 MEN1 (0.41) GAAPOLBNR1I2OPRM1DRD3
SCHEMBL38650963 0.86 NR1I2 (0.38) CYP1A2CYP2C9CYP2C19HTTNR1I2
SCHEMBL38650882 0.86 NR1I2 (0.39) NR1I2OPRM1DRD3OPRD1EGFR
SCHEMBL38650718 0.85 MAPT (0.38) NR1I2OPRM1DRD3OPRD1EGFR
SCHEMBL38650983 0.85 HTT (0.39) CYP1A2CYP2C9CYP2C19HTTGAA
SCHEMBL38650826 0.85 ALDH1A1 (0.42) CYP1A2CYP2C9CYP2C19HTTCTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010870-A Ester group substitution dibenzothio of (C) Synthesis method of azepine derivative 新疆大学 2026-05-12 CN disclosed